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ProteomicsIdentification of novel Coronin 1A interacting proteins
Severe combined immunodeficiency 8 (IMD8) is caused by mutations in the human Coronin 1A (Coro1A). The clinical presentation of IMD8 patients is characterized by recurrent bacterial infections, suggesting an important role of Coro1A in innate immunity. To analyze the molecular mechanism of Coro1A du...
ORGANISM(S): Homo sapiens (Human) 
2017-06-29 | PXD004635 | Pride
Hl-60 cells Gfp nanotraps Maxquant Coronin 1a Co-immunoprecipitation Lc-ms/ms 
ProteomicsT Lymphocytes induce the expression of Coronin-1A in breast cancer cells enabling the transmigration through a blood-brain-barrier model
Background: In previous work we discovered that T lymphocytes play a prominent role in the rise of brain metastases of ER-negative breast cancers. In the present study we explored expressional changes due to T cell contact associated with penetration through the BBB for breast cancer cell lines deri...
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD053787 | Pride
Breast cancer  brain metastasis  blood-brain barrier  proteomics  liquid chromatography-mass spectrometry  coronin-1a 
UnknownCoronin 1A facilitates calcium mobilization and promotes astrocyte reactivity in HIV-1 neuropathogenesis.
Not available
S-EPMC8984076 | biostudies-literature
UnknownMast cell function is not altered by Coronin-1A deficiency.
Not available
S-EPMC2974433 | biostudies-literature
UnknownCoronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling.
Not available
S-EPMC2568942 | biostudies-literature
UnknownActin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K.
Not available
S-EPMC5353622 | biostudies-literature
UnknownProteome of acidic phospholipid-binding proteins: spatial and temporal regulation of Coronin 1A by phosphoinositides.
Not available
S-EPMC2825472 | biostudies-literature
UnknownThe lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation.
Not available
S-EPMC2274909 | biostudies-literature
UnknownSerum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers.
Not available
S-EPMC9402777 | biostudies-literature
TranscriptomicsIFN-γ and IL-17 synergistic anti-mycobacterial response via coronin-1A inhibition
This study investigates the molecular mechanism underlying the synergistic anti-mycobacterial effect of IFN-γ and IL-17. We performed microarray analysis on bone marrow-derived macrophages (BMDMs) from C57BL/6J mice infected with Mycobacterium tuberculosis H37Rv and treated with infection control, I...
ORGANISM(S): Mus musculus 
2025-11-11 | E-MTAB-16005 | biostudies-arrayexpress
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