crsipr-cas9 - OmicsDI

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Genomics (9)
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Mus musculus (4)
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EFO:0001352 (4)
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Nostoc sp. PCC 7120 = FACHB-418 (4)
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Viruses (4)
Homo sapiens (2)

Organisms

Mus musculus (5)
Homo sapiens (3)

Repository

ENA (9)
geo (5)
pride (4)
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Tissue

Endosperm (4)

Technology Type

Mass Spectrometry (4)
Shotgun proteomics (3)
Mass spectrometry (1)
SWATH MS (1)

Instrument Platform

NextSeq 500 (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2022 (6)
2023 (3)
2025 (1)
2024 (1)

CHEBI ID

CHEBI:189528 (1)
CHEBI:189523 (1)
CHEBI:189519 (1)
CHEBI:189515 (1)
CHEBI:189507 (1)
CHEBI:189506 (1)
CHEBI:189505 (1)
CHEBI:189504 (1)
CHEBI:189503 (1)
CHEBI:189502 (1)
CHEBI:189500 (1)
CHEBI:189499 (1)
CHEBI:189493 (1)
CHEBI:189492 (1)
CHEBI:189490 (1)
CHEBI:189484 (1)
CHEBI:189483 (1)
CHEBI:189481 (1)
CHEBI:189480 (1)
CHEBI:189479 (1)
CHEBI:189478 (1)
CHEBI:189475 (1)
CHEBI:189473 (1)
CHEBI:189470 (1)
CHEBI:189468 (1)
CHEBI:189464 (1)
CHEBI:181507 (1)
CHEBI:167750 (1)
CHEBI:167818 (1)
CHEBI:182243 (1)

Metabolite Name

1-({(1s,4s,6s)-6-isopropyl-3-methyl-4-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-2-cyclohexen-1-yl}methyl)-3-(3-methoxyphenyl)urea (1)
N-({(2r,4s,5r)-5-[3-(3,4-dimethoxyphenyl)-1-methyl-1h-pyrazol-5-yl]-1-azabicyclo[2.2.2]oct-2-yl}methyl)-2-ethylbutanamide (1)
6-o-[(2e)-3-(4-hydroxyphenyl)-2-propenoyl]-1-o-[(2e)-3-phenyl-2-propenoyl]-beta-d-glucopyranose (1)
4-methoxybenzaldehyde n-[6-(tert-butyl)thieno[3,2-d]pyrimidin-4-yl]hydrazone (1)
4-(4-chlorophenyl)-n-(2-pyridinylmethyl)cyclohexanecarboxamide (1)
4h-1-benzopyran-4-one, 6-beta-d-glucopyranosyl-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (s)- (Hemiphloin) (1)
(3r,4s)-4,6,8-trihydroxy-7-methoxy-3-methyl-3,4-dihydro-1h-isochromen-1-one (1)
1,4:3,6-dianhydro-2,5-dideoxy-2-{[4-(3-fluorophenyl)-2-pyrimidinyl]amino}-5-[(methoxyacetyl)amino]-l-iditol (1)
Cetirizine n-oxide (1)
Adb-pinaca pentanoic acid metabolite (1)
5,8-dihydroxy-4-oxo-1,2,3,4-tetrahydro-1-naphthalenyl 6-o-(3,4,5-trihydroxybenzoyl)-beta-d-glucopyranoside (1)
Methyl (1s,4ar,6s,7r,7as)-1-(beta-d-glucopyranosyloxy)-4a,7-dihydroxy-6-{[(2e)-3-(4-hydroxyphenyl)-2-propenoyl]oxy}-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate (1)
Methyl 4-{2-cyano-2-[(4-methylphenyl)sulfonyl]vinyl}-2,5-dimethyl-1h-pyrrole-3-carboxylate (1)
N-[(6as,8s)-2-(2,3-dimethylphenyl)-6,12-dioxo-5,6,6a,7,8,9,10,12-octahydropyrido[2,1-c][1,4]benzodiazepin-8-yl]nicotinamide (1)
4-[4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1h,3h-furo[3,4-c]furan-1-yl]-2-methoxyphenyl hexopyranoside (1)
4-[(1s,3as,4r,6ar)-3a-hydroxy-4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1h,3h-furo[3,4-c]furan-1-yl]-2-methoxyphenyl beta-d-glucopyranoside (1)
N4-acetyl sulfamethazine (1)
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-o-(6-deoxyhexopyranosyl)-4-o-[(2e)-3-(4-hydroxyphenyl)-2-propenoyl]hexopyranoside (1)
Fr 145237 (1)
Ethyl {(1s,4s,5s)-4-[(isonicotinoylamino)methyl]-5-isopropyl-2-methyl-2-cyclohexen-1-yl}acetate (1)
2-hydroxy-4-(4-hydroxyphenyl)butanoic acid (1)
2-(tert-butylsulfonyl)-3-(3-methylbenzo[b]thiophen-2-yl)acrylonitrile (1)
Liguiritigenin-7-O-beta-D-apiosyl-4'-O-beta-D-glucoside (1)
2-hydroxy-4-methoxy-3-(3-methyl-2-buten-1-yl)-6-[(e)-2-phenylvinyl]benzoic acid (1)
N-(2-fluorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide (1)
Metazachlor-esa (1)
Aica ribonucleotide (1)
2-[(3s)-1-(cyclohexylmethyl)-3-pyrrolidinyl]-5-fluoro-1h-benzimidazole (1)
N-(4-{(2r,3r)-3-(hydroxymethyl)-4-[(1-methyl-1h-imidazol-2-yl)methyl]-5-oxo-2-morpholinyl}phenyl)-2-methylpropanamide (1)
Isopropyl 4-Hydroxybenzoate (1)

First Public Date

2023 (3)
2025 (2)
2024 (2)
2026 (1)
2020 (1)

Study type

RNA-seq of coding RNA from single cells (1)

Release Date

2023 (3)
2022 (2)
2019 (2)
2025 (1)
2021 (1)
2020 (1)
2018 (1)
2017 (1)
2016 (1)
2015 (1)

Lab affiliation

Department of Bioactive and Functional Food Chemistry, Institute of Applied Biosciences, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany (2)
AGES - Austrian Agency for Health and Food Safety, Institute for Animal Nutrition and Feed, Vienna, Austria (1)
Core Facility Mass Spectrometry BOKU, University of Natural Resources and Life Sciences, Vienna, Austria (1)

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Sexually dimorphic effects of ADNP mutation and Davunotide treatment on mice hippocampal transcriptome

ADNP haplo-insufficient (Adnp +/- ) mice or CRSIPR/Cas9 edited to carry the most prevalent neurodevelopmental ADNP syndrome mutation, p.Tyr718*. A subgroup was treated the ADNP fragment, investigational drug, NAP (davunetide).

ORGANISM(S): Mus musculus

2025-05-30 | GSE272331 | GEO

Nano-Polymers as Cas9 Inhibitors.

Not available

S-EPMC11820846 | biostudies-literature

Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos.

Not available

S-EPMC5290468 | biostudies-literature

CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B.

Not available

S-EPMC5801905 | biostudies-literature

Expanding the CRISPR/Cas9 toolkit for Pichia pastoris with efficient donor integration and alternative resistance markers.