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ProteomicsPRAME and CTCFL-reactive TCRs for the treatment of ovarian cancer
Recurrent disease emerges in the majority of patients with ovarian cancer (OVCA). Adoptive T-cell therapies with T-cell receptors (TCRs) targeting tumor-associated antigens (TAAs) are considered promising solutions for less-immunogenic ‘cold’ ovarian tumors. In order to treat a broader patient popul...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD040651 | Pride
Ovarian cancer  prame  ctcfl  cldn6  tcr gene transfer  t-cell therapy  immunotherapy  peptide  allogeneic hla 
GenomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [ChIP-Seq]
CTCF and CTCFL DNA binding profile in CTCFL induced and non-induced ES cells.CTCF is a highly conserved and essential zinc finger protein that in conjunction with cohesin organizes chromatin into loops, thereby regulating gene expression and epigenetic events. The function of CTCFL or BORIS, the tes...
ORGANISM(S): Mus musculus 
2012-07-25 | E-GEOD-34094 | biostudies-arrayexpress
TranscriptomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [MoGene-1_0 Expression]
CTCFL binding to DNA and the effect of CTCFL expression in ES cells RNA extracted from CTCFL induced and non-induced ES cells was hybridized on Affymetrix Mouse Gene 1.0ST arrays
ORGANISM(S): Mus musculus 
2012-07-24 | E-GEOD-34092 | biostudies-arrayexpress
GenomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF
This SuperSeries is composed of the following subset Series: GSE34091: Nucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [Mouse430_2 Expression] GSE34092: Nucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTC...
ORGANISM(S): Mus musculus 
2012-07-24 | E-GEOD-34093 | biostudies-arrayexpress
TranscriptomicsNucleosome dynamics specifies genome-wide binding of the male germ cell gene regulator CTCFL and of CTCF [Mouse430_2 Expression]
The effect of CTCFL mutation on the transcriptional program in testes Testis RNA extracted from CTCFL wildtype and mutant mice was hybridized on Affymetrix Mouse430_2 arrays
ORGANISM(S): Mus musculus 
2012-07-24 | E-GEOD-34091 | biostudies-arrayexpress
GenomicsMus musculus strain:Ctcfl transgenic
Ctcfl transgene induction in ES cells gene expression analysis
PRJNA291044 | ENA
GenomicsCTCFL
CTCFL
PRJNA400477 | ENA
TranscriptomicsRNA-Seq of Ctcfl transgenic mouse ES cells
Ctcfl, a paralog of Ctcf, also known as BORIS (Brother of Regulator of Imprinted Sites), is a testis expressed gene whose function is largely unknown. As a cancer testis antigen, it is often expressed in tumor cells and also seen in two benign human vascular malformations, juvenile angiofibromas (JA...
ORGANISM(S): Mus musculus 
2015-08-19 | GSE72178 | GEO
GenomicsDefining the relative and combined contribution of CTCF and CTCFL to genomic regulation
Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation
PRJNA589339 | ENA
UnknownDefining the relative and combined contribution of CTCF and CTCFL to genomic regulation.
Not available
S-EPMC7212617 | biostudies-literature
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