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ProteomicsHeptad-specific phosphorylation of RNA polymerase II CTD
The carboxy-terminal domain (CTD) of RNA polymerase II (Pol II) consists of heptad repeats with the consensus motif Y1-S2-P3-T4-S5-P6-S7. Dynamic phosphorylation of the CTD coordinates Pol II progression through the transcription cycle. Monoclonal antibodies have been used to study in vivo the poten...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2016-01-25 | PXD003159 | Pride
Pol ii ctd  ctd heptads  ctd phosphosites  lc-ms/ms 
GenomicsCombinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
C-terminal domain (CTD) of RNA polymerase II is crucial for recruiting transcription regulators via specific post-translational modifications (PTM), especially phosphorylation. The hypothesis of combination of PTMs, or ‘CTD code’, that can allow precise and dynamic recruitment of transcription machi...
ORGANISM(S): Homo sapiens 
2025-01-16 | GSE286258 | GEO
GenomicsCombinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
C-terminal domain (CTD) of RNA polymerase II is crucial for recruiting transcription regulators via specific post-translational modifications (PTM), especially phosphorylation. The hypothesis of combination of PTMs, or ‘CTD code’, that can allow precise and dynamic recruitment of transcription machi...
ORGANISM(S): Homo sapiens 
2025-01-16 | GSE286362 | GEO
ProteomicsCombinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
C-terminal domain (CTD) of RNA polymerase II is crucial for recruiting transcription regulators via specific post-translational modifications (PTM), especially phosphorylation. The hypothesis of combination of PTMs, or CTD code, that can allow precise and dynamic recruitment of transcription machine...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-01-11 | MSV000096830 | MassIVE
OtherDecoding a combinatorial RNA polymerase II CTD grammar that specifies protein-coding gene transcription and mRNA export [TT-seq]
The C-terminal domain (CTD) of RNA polymerase II orchestrates transcription via specific post-translational modifications (PTMs), notably phosphorylation. The combinatorial phosphorylation of CTD can potentially encode the precise recruitment of transcription machinery but lacks robust evidence. Add...
ORGANISM(S): Homo sapiens 
2026-03-19 | GSE324962 | GEO
GenomicsDecoding a combinatorial RNA polymerase II CTD grammar that specifies protein-coding gene transcription and mRNA export [ChIP-seq]
The C-terminal domain (CTD) of RNA polymerase II orchestrates transcription via specific post-translational modifications (PTMs), notably phosphorylation. The combinatorial phosphorylation of CTD can potentially encode the precise recruitment of transcription machinery, but lacks robust evidence. Ad...
ORGANISM(S): Homo sapiens 
2026-03-18 | GSE324921 | GEO
GenomicsCombinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
Combinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
PRJNA1208980 | ENA
GenomicsCombinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
Combinatorial phosphorylation on CTD of RNA polymerase II selectively controls transcription and export of protein-coding mRNAs
PRJNA1208493 | ENA
GenomicsDecoding a combinatorial RNA polymerase II CTD grammar that specifies protein-coding gene transcription and mRNA export [TT-seq]
Decoding a combinatorial RNA polymerase II CTD grammar that specifies protein-coding gene transcription and mRNA export [TT-seq]
PRJNA1438170 | ENA
GenomicsDecoding a combinatorial RNA polymerase II CTD grammar that specifies protein-coding gene transcription and mRNA export [ChIP-seq]
Decoding a combinatorial RNA polymerase II CTD grammar that specifies protein-coding gene transcription and mRNA export [ChIP-seq]
PRJNA1438100 | ENA
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