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MetabolomicsMuRF1-Related Metabolic Alterations in HL-1 Cardiomyocyte Induced by Cyclic Stretch
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ORGANISM(S): Mus musculus 
ST000924 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human bladder smooth muscle cells subjected to cyclic stretch-relaxation
The aim of the experiment was to determine the effect of cyclic stretch-relaxation ("stretch") on gene expression patterns in normal diploid human bladder smooth muscle cells. Cells plated on silicone elastomer bottomed 6-well culture dishes were grown to ~80% confluence, serum-depleted for 48h and ...
ORGANISM(S): Homo sapiens 
2007-08-04 | E-GEOD-1595 | biostudies-arrayexpress
TranscriptomicsExpression data from static and cyclic stretched porcine aortic heart valves
We explored the hypothesis that Serotonin (5HT) receptor signaling, that can be enhanced with 5HT transporter blockade with Fluoxetine (Fluox), in the aortic valve may vary based upon the biomechanical activity of the aortic valve leaflet. We used Affymetrix microarrays to study gene expression prof...
ORGANISM(S): Sus scrofa 
2010-05-27 | E-GEOD-21663 | biostudies-arrayexpress
ProteomicsPhosphoproteome of cyclic stretch A549 and IMR-90
Lung cancer is one of the leading causes of death. However, most of the researches were based on the traditional cell-culturing method. Whereas cells of lung are subjected to the mechanical forces periodically while breathing. In the present study, we applied cyclic stretch to stimulate the continuo...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD012010 | Pride
Phosphoproteome  cyclic stretch  lund cancer  lung fibroblast 
TranscriptomicsRearrangement of actin stress fiber in HUVECs under cyclic stretch
Time-course of gene profiles indicate that gene expression changing in cyclic stretch are related to cell adhesion and MAPK signaling. Gene expression changing by uniaxiali stretch was studied in a time course assay within 1.5 hour. Six time points (0, 10, 20, 30, 60, 90 min) were triplicated
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-16004 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human A549 cell line activated with either cyclic stretch (20% elongation), tumor necrosis factor or lipopolysaccharide
Alveolar epithalial cells (A549) were used as a model of pulmonary parenchymal cell activation to quiery gene expression profile of activation with either cyclic stretch (20% elongation), TNF (20 ng/ml), LPS (1 mcg/ml) or TNF+STRETCH at both 1 and 4 hrs.
ORGANISM(S): Homo sapiens 
2007-08-04 | E-GEOD-1541 | biostudies-arrayexpress
TranscriptomicsComparison of human aortic valve interstitial cells (AVICs) exposed to cyclic stretch to static samples
AVICs were exposed to cyclic stretch to examine the role of mechanical stimuli on gene expression AVICs cultured on collagen 1 coated Bioflex were exposed to 14% stretch at 1 hz or static conditions using a Flexcell-5000 14% stretch was the experimental condition while the static condition was the c...
ORGANISM(S): Homo sapiens 
2015-01-09 | E-GEOD-47687 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human bronchial epithelial cells exposed to cyclic stretch with and without LPS or TNFa
Acute respiratory distress syndrome (ARDS) is a catastrophic form of acute lung injury (ALI). The necessity for mechanical ventilation (MV) renders patients at risk for ventilator induced lung injury (VILI). Exposure to repetitive cyclic stretch (CS) and/or over-inflation exacerbates injury. Reducin...
ORGANISM(S): Homo sapiens 
2009-09-15 | E-GEOD-16650 | biostudies-arrayexpress
TranscriptomicsStretch-dependent genes in vascular smooth muscle cells
Vascular smooth muscle cells (VSMCs) respond to biomechanical stretch with specific changes in gene expression which govern the phenotype of these cells. The mechanotransducer zyxin is a potential candidate for regulating the expression of such genes. Using microarrays, we compared stretch-induced ...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-60447 | biostudies-arrayexpress
GenomicsLack of cyclic stretch disturbs endothelial cell transcriptomic profile
Lack of cyclic stretch disturbs endothelial cell transcriptomic profile
PRJNA923636 | ENA
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