d-serine - OmicsDI

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Transcriptomics (2730)
Unknown (1446)
Metabolomics (619)
Genomics (577)
Proteomics (381)
Models (9)
Other (9)
Multiomics (8)

Organisms

Homo sapiens (1476)
Mus musculus (886)
Saccharomyces cerevisiae (138)
Rattus norvegicus (112)
Drosophila melanogaster (111)
Arabidopsis thaliana (82)
Caenorhabditis elegans (38)
Schizosaccharomyces pombe (29)
Danio rerio (27)
Candida albicans (25)
Gallus gallus (23)
Escherichia coli (15)
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Canis lupus familiaris (12)
Mycobacterium tuberculosis (10)
Sus scrofa (10)
Escherichia coli str. K-12 substr. MG1655 (8)
Oryza sativa (8)
Bacillus subtilis subsp. subtilis str. 168 (6)
Streptococcus agalactiae (6)
Bacillus subtilis (6)
Saccharomyces cerevisiae S288C (6)
Salmonella enterica subsp. enterica serovar Typhimurium (6)
Pseudomonas aeruginosa (6)
Zea mays (5)
Nicotiana tabacum (5)
Mycobacterium tuberculosis H37Rv (5)
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 (4)
Tetrahymena thermophila (3)
Bos indicus (3)

Organisms

Mus musculus (33)
Homo sapiens (23)
Drosophila melanogaster (3)
Rattus norvegicus (2)
Saccharomyces cerevisiae (2)
Agrobacterium fabrum str. C58 (1)
Diutina catenulata (1)
Daphnia sinensis (1)
Rat adeno-associated virus (1)
Haloferax volcanii DS2 (1)
Bacillus tequilensis (1)
Clostridioides difficile R20291 (1)
Debaryomyces hansenii (1)
Escherichia coli (1)
Danio rerio (1)
Bos taurus (1)

Repository

biostudies-arrayexpress (2964)
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ENA (98)
pride (97)
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geo (56)
iProX (25)
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GPMDB (2)
ExpressionAtlas (1)
BioModels (1)

Tissue

Blood (116)
Cultured cells (47)
Liver (23)
Feces (22)
Urine (15)
Macrophages (14)
Muscle (14)
Bacterial cells (14)
Plant (13)
Heart (10)
Cells (9)
Brain (9)
Kidney (9)
Lung (9)
Unspecified (8)
Intestine (6)
Stem cells (5)
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Cerebrospinal fluid (5)
Fibroblast cells (4)
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Plasmodium cells (3)
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Disease

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Hyperglycaemic (2)
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Pancreatic cancer (2)
Astrocytoma (1)
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Cataract (1)
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Acute erythroid leukemia (1)
Alzheimer's disease (1)
Not applicable (1)
Rett syndrome (1)
Keratoconus (1)
Ischaemia reperfusion injury (1)
Pneumococcal meningitis (1)
Insulin resistance (1)
Apparently healthy (1)
"hepatocellular adenoma" (1)
Liposarcoma (1)
Non-diseased (1)
Dukes D primary colon cancer (1)
Giant cell glioblastoma (1)
Colon cancer metastasis (1)
Rheumatoid arthritis (1)
Osteosarcoma (1)

Technology Type

Mass Spectrometry (507)
ESI (324)
Mass spectrometry (120)
EI (100)
Mass spectrometry assay (67)
NMR spectroscopy (14)
Illumina HiSeq 2000 (10)
NMR spectroscopy assay (4)
Illumina HiSeq 2500 (3)
Illumina MiSeq (3)
APCI (3)
Illumina HiSeq 2500, ILLUMINA (2)
Illumina HiSeq 2500, Illumina HiSeq 2000 (2)
Illumina Genome Analyzer II (2)
API (2)
NMR (2)
NextSeq 500, Illumina HiSeq 4000, ILLUMINA (1)
Illumina MiSeq, ILLUMINA (1)
Illumina HiScanSQ, ILLUMINA (1)
Illumina HiSeq 4000, ILLUMINA (1)
Illumina HiSeq 4000, Illumina HiSeq 2500, ILLUMINA (1)
Illumina_450K, Illumina_HumanHT-12_V4, ILLUMINA, Illumina HiSeq 2000 (1)
HumanOmni1 Quad BeadChip (1)
Illumina HiSeq 2000, Infinium HumanMethylation450 BeadChip (1)
HiSeq X Ten (1)
Illumina MiSeq, Illumina Genome Analyzer IIx (1)
Ion Torrent Proton, Illumina HiSeq 2000 (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Complete Genomics (1)
AB SOLiD System 3.0 (1)

Instrument Platform

NextSeq 500 (77)
Illumina NovaSeq 6000 (76)
Illumina HiSeq 2000 (41)
Illumina HiSeq 2500 (33)
Illumina HiSeq 4000 (28)
BGISEQ-500 (26)
NextSeq 550 (14)
Illumina MiSeq (13)
NextSeq 2000 (11)
Illumina NovaSeq X (9)
Illumina HiSeq 3000 (7)
DNBSEQ-T7 (6)
Illumina Genome Analyzer IIx (5)
NA (5)
Illumina HiSeq 1500 (5)
DNBSEQ-G400 (4)
MinION (4)
HiSeq X Ten (4)
GenePix 4000A [Axon Instruments] (3)
418 [Affymetrix] (3)
N/A (3)
Illumina HiSeq 1000 (3)
Sequel II (2)
Element AVITI (2)
MA900, Sony (2)
10x Chromium Controller (2)
Illumina Hiseq 2500 (2)
ScanArray 4000 [PerkinElmer] (2)
ScanArray [PerkinElmer] (2)
G2565AA DNA microarray scanner [Agilent] (2)

Publication Date

2013 (373)
2014 (357)
2010 (319)
2015 (303)
2012 (284)
2011 (256)
2008 (221)
2016 (218)
2026 (157)
2025 (151)
2009 (141)
2023 (127)
2022 (102)
2007 (91)
2021 (87)
2024 (80)
2018 (65)
2020 (60)
2017 (44)
2005 (44)
2019 (41)
2006 (21)
2004 (17)
2003 (1)
2002 (1)
2027 (1)

UNIPROT ID/AC

1433B_MOUSE (5)
1433E_MOUSE (5)
1433F_MOUSE (5)
1433G_MOUSE (5)
1433S_MOUSE (5)
1433T_MOUSE (5)
1433Z_MOUSE (5)
2A5A_MOUSE (5)
2AAA_MOUSE (5)
2ABA_MOUSE (5)
3HIDH_MOUSE (5)
4F2_MOUSE (5)
6PGD_MOUSE (5)
AAKG1_MOUSE (5)
AATC_MOUSE (5)
AATM_MOUSE (5)
ABCB7_MOUSE (5)
ABCC9_MOUSE (5)
ABCE1_MOUSE (5)
ABHDB_MOUSE (5)
ABHEB_MOUSE (5)
ABLM1_MOUSE (5)
ACAD8_MOUSE (5)
ACAD9_MOUSE (5)
ACADL_MOUSE (5)
ACADM_MOUSE (5)
Q8WUJ0 (1)
Q13115 (1)
P27361 (1)
Q02750 (1)

ENSEMBL ID

ENSG00000147251 (3)
ENSG00000170477 (3)
ENSG00000247315 (3)
ENSMUSG00000021039 (1)
ENSMUSG00000090272 (1)
ENSMUSG00000096833 (1)
ENSMUSP00000106991 (1)
ENSMUSP00000141097 (1)
ENSMUSP00000141542 (1)

CHEBI ID

CHEBI:30769 (42)
CHEBI:30915 (39)
CHEBI:15428 (37)
CHEBI:17295 (36)
CHEBI:16015 (35)
CHEBI:16919 (34)
CHEBI:15741 (33)
CHEBI:16335 (33)
CHEBI:15891 (33)
CHEBI:32816 (33)
CHEBI:15354 (33)
CHEBI:17895 (33)
CHEBI:17750 (32)
CHEBI:16857 (31)
CHEBI:17368 (31)
CHEBI:16708 (29)
CHEBI:16467 (29)
CHEBI:18012 (29)
CHEBI:17268 (28)
CHEBI:18050 (28)
CHEBI:15971 (28)
CHEBI:16737 (28)
CHEBI:25017 (27)
CHEBI:16235 (27)
CHEBI:17203 (27)
CHEBI:16704 (27)
CHEBI:17596 (27)
CHEBI:16811 (26)
CHEBI:28300 (26)
CHEBI:7916 (26)

Metabolite Name

Creatine (59)
Taurine (56)
Hypoxanthine (56)
Adenosine (52)
Uracil (50)
L-Phenylalanine (50)
Choline (49)
Inosine (49)
Betaine (47)
Adenine (47)
Xanthine (46)
Creatinine (46)
L-Histidine (45)
Guanine (45)
Azelaic acid (44)
L-Tyrosine (44)
Guanosine (43)
L-Threonine (42)
Cytosine (42)
D-Serine (41)
L-Proline (41)
L-Tryptophan (41)
L-Serine (41)
Uridine (40)
Glycine (39)
Thymine (39)
L-Arginine (39)
Riboflavin (38)
L-Glutamine (38)
Cytidine (38)

First Public Date

2025 (21)
2014 (14)
2022 (12)
2016 (11)
2026 (9)
2018 (6)
2024 (5)
2020 (5)
2023 (4)
2021 (3)
2019 (3)
2017 (2)
2013 (2)
2015 (1)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Department Biochemistry of Plant Interactions, Leibniz Institute of Plant Biochemistry, 06120 Halle (Saale), Germany (8)
Leibniz Institute of Plant Biochemistry, Department Biochemistry of Plant Interactions, Weinberg 3, 06120 Halle (Saale), Germany (6)
Department Biochemistry of Plant Interactions, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany (4)
Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong SAR, China (2)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (2)
Université de Montréal, Quebec, Canada (2)
1 Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, PR China 2 Department of Microbiology and Immunology, Tongji University School of Medicine, Shanghai 200049, PR China 3 Clinical Translation Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China. (1)
6Department of Molecular Science/UT Health Rio Grande Valley, USA (1)
Aix Marseille Univ, CNRS, INSERM, Institut Paoli-Calmettes, CRCM, Marseille, France (1)
Associate Professor Faculty of Biology Technion-Israel Institute of Technology, Technion City, Haifa 3200003, Israel (1)
Australian Centre for Ecogenomics, The University of Queensland (1)
Biomolecular Mass Spectrometry and Proteomics Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences Utrecht University Padualaan 8 3584 CH Utrecht The Netherlands, Janssen Infectious Diseases and Vaccines, Crucell Holland B.V., Leiden, the Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Boston Children's Hospital | Harvard Medical School (1)
CRUK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK. (1)
Cell Biology, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK. (1)
Chair of Proteomics and Bioanalytics Technische Universitaet Muenchen Partner Site of the German Cancer Consortium Emil Erlenmeyer Forum 5 85354 Freising Germany (1)
Computational and Experimental Biology Group NOVA MEDICAL SCHOOL / FACULDADE DE CIÊNCIAS MÉDICAS UNIVERSIDADE NOVA DE LISBOA Rua Câmara Pestana, 6-6A | 1150-082 Lisboa Portugal (1)
Corelabs, King Abdullah University of Science and Technology, Thuwal 23500-6900, Kingdom of Saudi Arabia (1)
DIVAS, Department of Veterinary Medicine and Animal Sciences (1)
DIVAS, University of Milan (1)
Department for Systems Biology, Institut de recherches cliniques de Montréal (IRCM), Montréal, QC, Canada Département de biochimie et médecine moléculaire, Universitéde Montréal, Montréal, QC, Canada Division of Experimental Medicine, McGill University, Montreal, QC, Canada (1)
Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA (1)
Department of Biochemistry, University of Washington, Seattle, WA, USA. Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA Institute for Protein Design, University of Washington, Seattle, WA, USA (1)
Department of Biological Sciences - University of Alberta (1)
Department of Biology, Institute of Molecular Plant Biology, Plant Biotechnology, ETH Zurich (1)
Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland (1)
Department of Chemistry, University of Illinois Chicago, Chicago, IL, USA (1)
Department of Genome Science, University of Washington, Seattle, USA (1)
Department of Genome Sciences, University of Washington (Seattle) (1)

IsPrivate

False (1)

Classification

bacteria (2)
viruses (1)

Modification

4x(2)H labeled dimethylated L-lysine (2)
4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (1764)
RNA-seq of coding RNA (381)
ChIP-seq (211)
ChIP-chip by tiling array (80)
Comparative genomic hybridization by array (58)
RNA-seq of non coding RNA (45)
Unknown experiment type (44)
Methylation profiling by array (42)
Other (41)
Transcription profiling by RT-PCR (31)
Methylation profiling by high throughput sequencing (27)
RNA-seq of coding RNA from single cells (26)
RNA-seq of total RNA (24)
DNA-seq (21)
ChIP-chip by array (20)
Genotyping by array (17)
Transcription profiling by tiling array (14)
Cell line - High-throughput sequencing (11)
ATAC-seq (11)
MicroRNA profiling by array (11)
Proteomic profiling by array (11)
High-throughput sequencing (7)
Animal - High-throughput sequencing (7)
RNAi profiling by array (6)
RIP-seq (5)
CUT&RUN (5)
Transcription profiling by SAGE (4)
MicroRNA profiling by high throughput sequencing (4)
Hi-C (4)
Genotyping by high throughput sequencing (3)

Release Date

2013 (420)
2014 (403)
2010 (368)
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2011 (306)
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2009 (177)
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2018 (117)
2024 (113)
2007 (112)
2019 (100)
2017 (89)
2026 (83)
2005 (50)
2006 (39)
2004 (31)
2003 (13)
2001 (9)
2002 (7)
1999 (7)
1998 (4)
2000 (3)
1996 (1)

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Expression data from brain tissue of Rattus norvegicus treated with D-Serine

d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxi...

ORGANISM(S): Rattus norvegicus

2008-03-08 | E-GEOD-10748 | biostudies-arrayexpress

Transcriptomics of TUV930 with D-Serine supplementation

PRJEB89299 | ENA

Transcriptomics of Nissle 1917 with D-Serine and/or D-Tyrosine supplementation

PRJEB89294 | ENA

Effect of D-serine on gene expression in Neuro2a cells

PRJNA1114685 | ENA

Transcriptional profile of D-serine tolerant EHEC mutants

EHEC TUV93-0 wild type and D-serine tolerant mutants were cultured in minimal medium with/without D-serine for 4 h 30 min, before harvesting for RNA-seq

PRJEB36550 | ENA

Mycobacterium tuberculosis produces D-serine under hypoxia to limit CD8+ T cell-dependent immunity in mice

Interferon (IFN)-γ-producing CD8+ T cells are involved in control of Mycobacterium tuberculosis (Mtb) infection, in part by promoting antimicrobial activities of macrophages. Whether Mtb counters these responses, particularly during the hypoxic conditions that arise within granulomas during infectio...

ORGANISM(S): Mycobacterium tuberculosis OFXR-32

2024-08-10 | PXD050258 | Pride

SLC38A2 mediates selective L-serine influx across the blood-brain barrier and controls brain D-serine and excitatory synapse development

PRJNA1462775 | ENA

D-Serine activates glycolysis via mTOR pathway in kidney remodeling and suppresses onset of diabetes

PRJNA649903 | ENA

Effect of D-serine on gene expression in Neuro2a cells

Serine metabolism provides essential metabolites for cellular growth and proliferation, and also produces neurotransmitters. However, how serine metabolism coordinates with functional development of neurons remains unclear. We report neurotransmitter D-serine inhibit growth of immature cells. Metabo...

ORGANISM(S): Mus musculus

2024-12-01 | GSE268106 | GEO

RNASeq of Escherichia coli O157:H7 in the presence of D-serine

The host metabolite D-serine contributes to bacterial niche specificity through gene selection.

PRJEB7974 | ENA

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