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TranscriptomicsRole of Histone Ubiquitylation and Deubiquitylation as Determined by the Analysis of an HTB1_K123R S. cerevisiae Strain
In Saccharomyces cerevisiae histone H2B is ubiquitylated at lysine 123. The SAGA complex component, Ubp8, is one of two proteases that remove this ubiquitin moiety. We analyzed gene expression in a strain containing a variant of histone H2B with lysine 123 converted to arginine to address the mechan...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-15 | E-GEOD-6316 | biostudies-arrayexpress
GenomicsA combinatorial ubiquitin code degrades substrates protected by deubiquitylation
A combinatorial ubiquitin code degrades substrates protected by deubiquitylation
PRJNA1141143 | ENA
UnknownDeubiquitylation regulates activation and proteolytic cleavage of ENaC.
Not available
S-EPMC2573013 | biostudies-literature
UnknownUV damage-induced RNA polymerase II stalling stimulates H2B deubiquitylation.
Not available
S-EPMC4156752 | biostudies-literature
UnknownDeubiquitylation and stabilization of PTEN by USP13.
Not available
S-EPMC3951854 | biostudies-literature
ProteomicsThe 19S RP-associated deubiquitylation downstream of AP-3β disassembles heat-induced stress granules in plants
To survive under adverse conditions, plants form stress granules (SGs) to temporally store mRNA and halt translation as a primary response. Dysregulation in SG disassembly can have detrimental effects on plant survival after stress release, yet the underlying mechanism remains poorly understood in p...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-01-24 | PXD054299 | Pride
Stress granules (sgs)  ap-3β  19s rp  deubiquitylation  non-proteolytic function 
ProteomicsThe adaptor protein AP-3β disassembles heat-induced stress granules via 19S RP-associated deubiquitylation in Arabidopsis
To survive under adverse conditions, plants form stress granules (SGs) to temporally store mRNA and halt translation as a primary response. Dysregulation in SG disassembly can have detrimental effects on plant survival after stress release, yet the underlying mechanism remains poorly understood. Usi...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-01-24 | PXD058194 | Pride
Stress granules  ap-3β  tsn1/2  19s rp  deubiquitylation 
TranscriptomicsA combinatorial ubiquitin code degrades substrates protected by deubiquitylation
Reversibility of protein ubiquitylation play essential roles in cellular protein homeostasis. How substrates stabilized by deubiquitylation are directed for degradation remains largely elusive. Here, we show that the branched ubiquitin chains promote the degradation of the deubiquitylase (DUB) OTUD5...
ORGANISM(S): Homo sapiens 
2025-02-19 | GSE273273 | GEO
UnknownCrystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11.
Not available
S-EPMC3939901 | biostudies-literature
UnknownUSP4 Auto-Deubiquitylation Promotes Homologous Recombination.
Not available
S-EPMC4643306 | biostudies-literature
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