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Many polyphenols have been recognized for their antioxidant and health benefits. The present study attempted, for the first time, to determine the effects of daily oral intake of β-cyclodextrin-encapsulated hydroxytyrosol (HT) on plasma platelet reactivity and proteomic and metabolomic profiles of p...
2025-06-30 | MTBLS12336 | MetaboLights
Nutritional and genetic risk factors for intestinal tumors are additive on mouse tumor phenotypes, demonstrating that diet and genetic factors impact risk by distinct combinatorial mechanisms. We analyzed expression profiles of small intestine crypts and villi from mice with nutritional and genetic ...
ORGANISM(S): Mus musculus 
There is a need to understand genetic and lifestyle factors that may influence the risk of cancer progression in men who have organ-confined prostate cancer and have chosen a programme of 'active surveillance' as opposed to radical treatment with the associated health risks. Epidemiological studies ...
ORGANISM(S): Homo sapiens 
Pancreatic cancer is a rare but fatal form of cancer, the fourth highest in absolute mortality. The main reason for the high mortality is late detection, caused in part by an incomplete understanding of the initiating factors. Known risk factors include obesity, diet and type 2 diabetes, however the...
ORGANISM(S): Mus musculus 
Inherited genetic risk factors play an important role in cancer. However, other than cancer susceptibility genes found in familial cancer syndromes and inherited in a Mendelian fashion, little is known about modifier genes (germline variants that interact with each other and with environmental facto...
ORGANISM(S): Mus musculus 
Epidemiological studies provide strong evidence that consumption of cruciferous vegetables, such as broccoli, can significantly reduce the risk of developing cancers. Sulforaphane (SFN), a phytochemical derived from cruciferous vegetables, induces anti-proliferative and pro-apoptotic responses in pr...
ORGANISM(S): Homo sapiens 
Besides smoking and exposure to specific environmental risk factors, also diet and in particular red meat consumption/exposure are described as risk factors contributing to lung cancer development. Incidence of non-smoking associated lung cancer is rising rapidly, globally. Global epidemiology supp...
ORGANISM(S): Homo sapiens (Human) 
2026-06-03 | PXD077096 | Pride
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