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MetabolomicsElucidation of the epitranscriptomic RNA modification landscape of chikungunya virus

The genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of viral RNA modification in infected human cells. ...

2024-06-11 | MTBLS8697 | MetaboLights
TranscriptomicsAdenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation
Adenosine-to-inosine (A-to-I) RNA editing, which is catalyzed by a family of adenosine deaminase acting on RNA (ADAR) enzymes, is important in the epitranscriptomic regulation of RNA metabolism. However, the role of A-to-I RNA editing in vascular disease is unknown. Here we show that cathepsin S mRN...
ORGANISM(S): Homo sapiens 
2016-09-05 | E-GEOD-60217 | biostudies-arrayexpress
UnknownEpitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
Not available
S-EPMC8287920 | biostudies-literature
UnknownEpitranscriptomic profiling across cell types reveals associations between APOBEC1-mediated RNA editing, gene expression outcomes, and cellular function.
Not available
S-EPMC5740640 | biostudies-literature
ProteomicsEpitranscriptomic editing screening identifies functional m6A Sites
This dataset supports the identification of proteins associated with CHD9 by immunoprecipitation-mass spectrometry (IP-MS) in prostate cancer cells. Endogenous CHD9 was enriched using anti-CHD9 antibodies (with IgG controls), and co-enriched proteins were identified by LC-MS/MS. The resulting protei...
ORGANISM(S): Homo sapiens (Human) 
2026-01-01 | PXD072235 | Pride
M6a  prostate cancer  epitranscriptomic editing  crispr screening  prostate cancer 
UnknownEpigenetic and epitranscriptomic role of lncRNA in carcinogenesis (Review).
Not available
S-EPMC11900940 | biostudies-literature
GenomicsMETTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers
METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers
PRJNA1013485 | ENA
UnknownEpitranscriptomic investigation of myopia-associated RNA editing in the retina.
Not available
S-EPMC10336353 | biostudies-literature
UnknownEpitranscriptomic subtyping, visualization, and denoising by global motif visualization.
Not available
S-EPMC10517956 | biostudies-literature
UnknownBrain Epitranscriptomic Analysis Revealed Altered A-to-I RNA Editing in Septic Patients.
Not available
S-EPMC9086164 | biostudies-literature
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