epstein barr virus

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Unknown (4080)
Transcriptomics (3943)
Genomics (875)
Proteomics (87)
Other (57)
Methylation profiling (17)
Clinical (6)
Metabolomics (6)
Genomic (4)
Multiomics (2)

Organisms

Homo sapiens (2152)
Mus musculus (1001)
Rattus norvegicus (119)
Arabidopsis thaliana (86)
Drosophila melanogaster (61)
Saccharomyces cerevisiae (57)
Sus scrofa (37)
Bos taurus (37)
Danio rerio (36)
Gallus gallus (31)
Caenorhabditis elegans (25)
Zea mays (18)
Oryza sativa (18)
Streptococcus pneumoniae D39 (16)
Escherichia coli (13)
Macaca mulatta (13)
Canis lupus familiaris (13)
Oryza sativa Japonica Group (12)
Schizosaccharomyces pombe (9)
Oncorhynchus mykiss (9)
Medicago truncatula (8)
Salmo salar (8)
Ovis aries (8)
Staphylococcus aureus (7)
Carassius auratus (6)
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Colinus virginianus (5)
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Mycobacterium tuberculosis H37Rv (5)
Boehmeria nivea (4)

Organisms

Homo sapiens (414)
Mus musculus (30)
human gammaherpesvirus 4 (26)
Callithrix jacchus (1)
Canis lupus familiaris (1)
metagenome (1)
Bos taurus (1)
Gallus gallus (1)
unidentified (1)

Repository

biostudies-arrayexpress (3765)
ENA (638)
geo (445)
EGA (57)
pride (39)
MassIVE (20)
MetaboLights (6)
jPOST (5)
dbGaP (4)
iProX (4)
ExpressionAtlas (3)
EVA (3)
PanoramaPublic (1)

Tissue

B cell (17)
Cell culture (13)
Blood (3)
Early embryonic cell (2)
Palatine tonsil (1)
Umbilical cord (1)
Acute myeloid leukemia cell line (1)
B-lymphoblastoid cell line (1)
B-lymphoblastoma cell (1)
Blood plasma (1)
Blood serum (1)
Brain (1)
Burkitt lymphoma cell (1)
Burkitt lymphoma cell line (1)
Cell suspension culture (1)
Cerebral cortex glial cell (1)
Cerebrospinal fluid (1)
Diffuse large B-cell lymphoma cell line (1)
Epithelial cell (1)
Erythrocyte (1)
Lymph node (1)
Lymphocyte (1)
Lymphocyte of B lineage (1)
Nasopharyngeal epithelial cell (1)
Peripheral blood mononuclear cell (1)
Permanent cell line cell (1)
RAJI cell (1)
Spleen (1)
T cell (1)
Thymus (1)

Disease

Oral squamous cell carcinoma (1)
Endometrium adenocarcinoma (1)
Gastric tubular adenocarcinoma (1)
Undifferentiated carcinoma (1)
Amelanotic melanoma (1)
Salivary gland squamous cell carcinoma (1)
Endometrial endometrioid adenocarcinoma, variant with squamous differentiation (1)
Ovarian endometrioid adenocarcinoma (1)
Gliosarcoma (1)
B-cell prolymphocytic leukemia (1)
Childhood acute monocytic leukemia (1)
Mucinous gastric adenocarcinoma (1)
Hereditary thyroid gland medullary carcinoma (1)
Extrarenal rhabdoid tumor (1)
Meningioma (1)
Leiomyoma, epithelioid (1)
Primary effusion lymphoma (1)
Cecum adenocarcinoma (1)
Bronchioloalveolar carcinoma (1)
Adenosquamous lung carcinoma (1)
Pancreatic adenosquamous carcinoma (1)
Laryngeal squamous cell carcinoma (1)
Duodenal adenocarcinoma (1)
Adult B acute lymphoblastic leukemia (1)
Uterine leiomyosarcoma (1)
Endometrial stromal sarcoma (1)
Chronic eosinophilic leukemia (1)
Ampulla of Vater adenocarcinoma (1)
Cutaneous melanoma (1)
Colon carcinoma (1)

Technology Type

Mass Spectrometry (39)
Shotgun proteomics (20)
Bottom-up proteomics (13)
Affinity purification coupled with mass spectrometry proteomics (4)
Data-dependent acquisition (4)
Mass spectrometry assay (3)
Illumina HiSeq 2000 (2)
Mass spectrometry (2)
Data-independent acquisition (2)
Gel-based experiment (2)
Immunopeptidomics (2)
NextSeq 500, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2500, ILLUMINA (1)
HiSeq X Ten (1)
Illumina HiSeq 2000, Illumina Genome Analyzer IIx (1)
Illumina HiSeq 2500 (1)
NMR spectroscopy (1)
Proteogenomics (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (28)
Illumina HiSeq 2500 (19)
Illumina HiSeq 2000 (16)
NextSeq 500 (11)
Illumina HiSeq 4000 (10)
Illumina HiSeq 1500 (9)
Illumina Genome Analyzer II (2)
Illumina NovaSeq X (2)
Illumina MiSeq (2)
NextSeq 550 (2)
10X Genomics Single Cell, V3.1 (1)
Agilent 2100 Bioanalyzer, Applied Biosystems 7900HT Sequence Detection System, Illumina TruSeq Small RNA Sample Preparation Kit (1)
RNeasy mini Kit, Ribo-Zero Human/Mouse/Rat kit (1)
Agilent Surescan High Resolution DNA microarray Scanner (1)
Beckman Coulter MoFlo Astrios (1)
Agilent G2565CA microarray scanner (1)
Solexa 2G Genome Analyzer (1)
BD FACSAria III (1)
Illumina iScan (1)
Agilent 2100 Bioanalyzer (1)
Illumina Genome Analyzer IIx (1)
G2565BA DNA microarray scanner [Agilent] (1)
GenePix 4000B [Axon Instruments] (1)
TruSeq (Illumina, Novogene, Genomic Centre Cambridge, CB4 0FW, UK.) (1)
NanoDrop spectrophotometer and the Agilent 2100 Bioanalyzer (1)
Histopaque-1077,FACSAria Fusion Sorter,Flow Cytometer (1)
NextSeq 2000 (1)
DNBSEQ-G400 (1)
MinION (1)
MassARRAY iPLEX (1)

Publication Date

2015 (655)
2010 (596)
2013 (530)
2014 (444)
2011 (439)
2012 (423)
2008 (201)
2016 (177)
2009 (157)
2007 (93)
2024 (70)
2021 (68)
2026 (65)
2025 (61)
2022 (54)
2019 (46)
2018 (39)
2017 (39)
2020 (35)
2023 (32)
2006 (25)
2005 (21)
2004 (12)
2003 (6)
2002 (2)

CHEBI ID

CHEBI:18237 (2)
CHEBI:32816 (2)
CHEBI:46171 (1)
CHEBI:21363 (1)
CHEBI:35766 (1)
CHEBI:84814 (1)
CHEBI:183109 (1)
CHEBI:165872 (1)
CHEBI:60312 (1)
CHEBI:36315 (1)
CHEBI:78266 (1)
CHEBI:84153 (1)
CHEBI:73218 (1)
CHEBI:78261 (1)
CHEBI:73209 (1)
CHEBI:75062 (1)
CHEBI:83053 (1)
CHEBI:15919 (1)
CHEBI:84829 (1)
CHEBI:33511 (1)
CHEBI:45696 (1)
CHEBI:133469 (1)
CHEBI:78647 (1)
CHEBI:44673 (1)
CHEBI:84415 (1)
CHEBI:45441 (1)
CHEBI:17768 (1)
CHEBI:138368 (1)
CHEBI:91315 (1)
CHEBI:82968 (1)

Metabolite Name

N-Acetyl-aspartic acid (2)
N2-Methylguanosine (2)
GTP (2)
Folic acid (2)
UDP-glucose (2)
2-Aminoadipic acid (2)
CTP (2)
HEPES (2)
Isoleucine (2)
Pantothenic acid (2)
N-Acetylneuraminic acid (2)
LPE 20:4 (2)
Taurine (2)
Cis-Aconitic acid (2)
Suberic acid (2)
Glucose (2)
Azelaic acid (2)
Glutamic acid (2)
Uric acid (2)
Xanthine (2)
Guanosine (2)
Uridine (2)
Pseudouridine (2)
Hippuric acid (2)
Ï«-Cyclodextrin (1)
PC O-18:1_16:0 (1)
LNAPE 22:4/N-18:0 (1)
LNAPE 16:0/N-20:0 (1)
PE O-18:0_22:4 (1)
PE O-17:1_22:6 (1)

First Public Date

2014 (87)
2025 (79)
2024 (77)
2026 (56)
2021 (48)
2019 (41)
2017 (41)
2023 (40)
2020 (40)
2018 (32)
2022 (31)
2015 (25)
2013 (24)
2016 (17)

Classification

viruses (26)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study status

Recruiting (2)
Completed (2)
No longer available (1)
Terminated (1)

Study type

Transcription profiling by array (2669)
RNA-seq of coding RNA (445)
Unknown experiment type (126)
RNA-seq of non coding RNA (92)
ChIP-seq (63)
Comparative genomic hybridization by array (59)
Other (55)
Methylation profiling by array (45)
ChIP-chip by tiling array (36)
Transcription profiling by SAGE (33)
Transcription profiling by RT-PCR (17)
Proteomic profiling by array (17)
Transcription profiling by tiling array (16)
RNA-seq of coding RNA from single cells (16)
Cell line - High-throughput sequencing (13)
Methylation profiling by high throughput sequencing (12)
Genotyping by array (10)
RNA-seq of total RNA (5)
Human - High-throughput sequencing (4)
ChIP-chip by array (4)
MicroRNA profiling by array (3)
Human - Single-cell sequencing (2)
High-throughput sequencing (2)
Human - One-color microarray (2)
RNAi profiling by array (2)
MicroRNA profiling by high throughput sequencing (2)
ATAC-seq (2)
DNA-seq (2)
ChIP-chip by SNP array (1)
Transcription profiling by MPSS (1)

Release Date

2015 (808)
2010 (674)
2013 (609)
2014 (559)
2012 (519)
2011 (516)
2022 (434)
2021 (407)
2025 (375)
2023 (360)
2020 (324)
2016 (316)
2024 (293)
2019 (292)
2018 (241)
2008 (239)
2017 (235)
2009 (219)
2007 (128)
2006 (54)
2026 (53)
2005 (45)
2004 (35)
2003 (28)
2001 (20)
1999 (19)
2002 (15)
2000 (14)
1998 (11)
1997 (3)

Lab affiliation

Cambridge Institute for Medical Research, Hills Road, Cambridge, CB2 0XY (2)
1 Department of Computer Science, Hanyang University, Seoul 04763, Republic of Korea 2 Institute for Artificial Intelligence Research, Hanyang University, Seoul 04763, Republic of Korea (1)
1Department of Hematology, Xiangya Hospital, Central South University, Changsha 410080, China 2NHC Key Laboratory of Carcinogenesis, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha 410078, China (1)
Cambridge Institute for Medical Research, University of Cambridge (1)
Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY (1)
Cancer Research Institute, Xiangya Basic Medical College, Central South University, No. 110 Xiangya Road, Kaifu District, Changsha City, Hunan Province (1)
Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA. (1)
Chair of Proteomics and Bioanalytics, Technical University of Munich, Emil-Erlenmeyer-Forum 5, D-85354, Freising, Germany Bavarian Center for Biomolecular Mass Spectrometry, Technical University of Munich, Gregor-Mendel-Strasse 4, D-85354, Freising, Germany (1)
Department of Biomedical sciences FSU College of Medicine (1)
Department of Human Genetics (1)
Department of Human Genetics University of Chicago (1)
Department of Human Genetics, University of Chicago, Chicago, Illinois, USA; Department of Medicine, University of Chicago, Chicago, Illinois, USA (1)
Department of Medicine II, Hematology/Oncology, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany (1)
Department of Microbiology and Molecular Genetics University of Pittsburgh (1)
Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University (1)
Department of Peptide-based Immunotherapy, Institute of Immunology, University and University Hospital Tübingen, Tübingen, Germany (1)
Florida State University College of Medicine (1)
Head Proteomics Group Leiden University Medical Center, Center for Proteomics and Metabolomics, The Netherlands (1)
Immunology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA (1)
Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallés, Barcelona, Spain. (1)
Institute for Cell Biology Dept. Immunology Auf der Morgenstelle 15, 72076 Tübingen Germany Partner Site of the German Cancer Consortium (1)
Institute for Research in Immunology and Cancer, Department of Chemistry, Université de Montréal, Montréal, Québec, Canada H3T 1J4 (1)
Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 3BX, United Kingdom (1)
Intercollegiate Faculty of Biotechnology, Laboratory of Mass Spectrometry, University of Gdańsk and Medical University of Gdańsk, Gdańsk, Poland (1)
Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München (1)
Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland (1)
Paul J Lehner PhD FRCP FMed Sci FRS Sheila Joan Smith Professor of Immunology Wellcome Principal Fellow and Honorary Consultant University of Cambridge CITIID Cambridge Biomedical Campus Cambridge CB2 0AW (1)
Pediatric Infectious Diseases Molecular Genetics and Microbiology Stony Brook University Life Sciences Building, Rm. 158 Stony Brook, NY 11794-5222 U.S.A. (1)
Philips Institute for Oral Health Research, VCU School of Dentistry, Virginia Commonwealth University, Richmond, Virginia 23298, USA (1)
ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Ghent University, B-9000 Ghent, Belgium (1)

Location

United States (4)
Italy (2)
Canada (2)
United Kingdom (2)
France (2)
Germany (1)
Spain (1)
Belgium (1)
Australia (1)
Austria (1)

Keyword

Epstein-Barr Virus (EBV) (2)
Allogeneic, Off-The-Shelf T-cell Immunotherapy (2)
Rapamune (1)
Neoral (1)
Prograf (1)
Brentuximab Vedotin (1)
STAR0602 (1)
Intravenous (1)
T Cell Receptor-targeting (1)
Bifunctional Antibody-Fusion (1)
Specific T Cell Activator (1)
Tumor Mutational Burden (TMB) High (1)
Microsatellite Instability (MSI) High (1)
Virally Associated Malignancies (1)
Checkpoint Inhibitor Resistance (1)
Immune Checkpoint Inhibitor Resistance (1)
Biliary Cancer (1)
Skin Squamous Cell Carcinoma (1)
Skin Basal Cell Carcinoma (1)
Small Bowel Cancer (1)
Solid Organ Transplant (HCT) (1)
Hematopoietic Cell Transplant (SOT) (1)
Primary Immunodeficiency (PID) (1)
Acquired Immunodeficiency (AID) (1)
Epstein-Barr Virus-associated Lymphoma (1)
HIV/AIDS Lymphoma (1)
Rheumatoid Arthritis and Lymphoma (1)
Tumor Necrosis Factor (TNF)-alpha Inhibitors and Lymphoma (1)
Inflammatory Bowel Disease and Lymphoma (1)
Epstein-Barr Virus-specific Cytotoxic T lymphocyte (EBV-CTL) (1)

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Ceramide Promotes Lytic Reactivation of Epstein-Barr Virus in Gastric Carcinoma

Epstein-Barr virus (EBV) has a lifelong latency period after initial infection. Rarely, however, when the EBV immediate early gene BZLF1 is expressed by a specific stimulus, the virus switches to the lytic cycle to produce progeny viruses. We found that EBV infection reduced levels of various cerami...

2023-12-20 | MTBLS7649 | MetaboLights

Characterization Epstein-Barr Virus-Associated Encephalitis via Identification of Metabolomic Biomarkers

Objective: Fulminant Epstein-Barr Virus (EBV) infection may lead to fatal outcomes in patients with EBV-associated encephalitis (EBVAE). To investigate potential biomarkers in EBVAE, we utilized an untargeted metabolomic methodology to identify disease-associated biomarkers in patients ...

2026-03-23 | MTBLS14111 | MetaboLights

Proteomics of EBV-infected lytic and refractory cells

Most humans are infected with Epstein-Barr virus (EBV), a cancer-causing virus. While EBV generally persists silently in B lymphocytes, periodic lytic (re-)activation of latent virus is central to its life cycle and to most EBV-related diseases. However, a substantial fraction of EBV-infected B cell...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-22 | MSV000079993 | MassIVE

A metabolic dependency of EBV can be targeted to hinder B cell transformation

Following infection of B cells, Epstein Barr virus (EBV) engages host pathways that mediate cell proliferation and transformation, contributing to the propensity of the virus to drive immune dysregulation and lymphomagenesis. We found that the EBV protein EBNA2 initiates NAD de novo bios...

2024-04-29 | MTBLS2243 | MetaboLights

ChIP-seq analysis with an antibody directed against the human H3K27ac protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1.

ChIP peaks were identified in both the human and viral genomes (genome assembly GRCh37 (hg19) and Epstein-Barr virus, Human Herpesvirus 4; GenBank accession KF717093.1).

ORGANISM(S): Homo sapiens

2021-06-22 | E-MTAB-8421 | biostudies-arrayexpress

DNA methylation epigenotype expanding to non-polycomb target genes, induced by Epstein-Barr virus infection in human gastric cancer

This SuperSeries is composed of the following subset Series: GSE31787: Aberrant DNA methylation epigenotype expanding to non-polycomb target genes, induced by Epstein-Barr virus infection in human gastric cancer [Affymetrix Expression] GSE31788: Aberrant DNA methylation epigenotype expanding to non-...

ORGANISM(S): Homo sapiens

2012-01-04 | E-GEOD-31789 | biostudies-arrayexpress

Epstein-Barr virus growth/latency III program alters cellular microRNA expression

The Epstein-Barr virus (EBV) is associated with lymphoid and epithelial cancers. Initial EBV infection alters lymphocyte gene expression, inducing cellular proliferation and differentiation as the virus transitions through consecutive latency transcription programs. Cellular microRNAs (miRNAs) are...

ORGANISM(S): Homo sapiens

2010-05-19 | E-GEOD-13056 | biostudies-arrayexpress

Genome-Wide Analysis of Host-Chromosome Binding Sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)

The Epstein-Barr Virus (EBV) Nuclear Antigen 1 (EBNA1) protein is required for the establishment of EBV latent infection in proliferating B-lymphocytes. EBNA1 is a multifunctional DNA-binding protein that stimulates DNA replication at the viral origin of plasmid replication (OriP), regulates transc...

ORGANISM(S): Homo sapiens

2011-07-16 | E-GEOD-30709 | biostudies-arrayexpress

Transcription profiling by array of human lymphocyte cells lines generated with EBNA3-knockout Epstein-Barr Viruses

Epstein-Barr virus (EBV) is able to drive the transformation of B-cells, resulting in the generation of lymphocyte cell lines (LCLs) in vitro. EBV nuclear proteins EBNA3A and EBNA3C are necessary for efficient transformation, while EBNA3B is dispensable. We describe a transcriptome analysis of LCLs ...

ORGANISM(S): Homo sapiens

2010-10-30 | E-MEXP-2768 | biostudies-arrayexpress

Epstein-Barr virus maintains lymphomas via its miRNAs

EpsteinM-bM-^@M-^PBarr virus (EBV) has evolved exquisite controls over its host cells, human B lymphocytes, not only directing these cells during latency to proliferate and thereby expand the pool of infected cells, but also to survive and thereby persist for the lifetime of the infected individual....

ORGANISM(S): Homo sapiens

2013-04-30 | E-GEOD-44769 | biostudies-arrayexpress

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