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Burkholderia sp. FERM BP-3421 Genome sequencing
We examined the transcriptional profile of human kidney biopsies, aiming to provide insight into the mechanisms of progressive CKD. This approach led to the identification of FERM domain protein 3, (FRMD3) as a molecular driver of disease. Transcriptome profiling was performed in human renal biopsy ...
ORGANISM(S): Homo sapiens (Human) 
2024-11-06 | PXD015297 | Pride
Pyk2 is a multidomain non-receptor tyrosine kinase that undergoes a complex, multi-stage activation process. Ca2+-flux induces conformational rearrangements that relieve autoinhibitory FERM domain interactions. The kinase domain phosphorylates a key linker residue to recruit Src kinase. Pyk2 and Src...
ORGANISM(S): Homo sapiens (Human) 
2023-03-08 | PXD034028 | Pride
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