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MetabolomicsEffect of Genetically Reduced Maternal Myostatin on Late Gestation Maternal, Fetal, and Placental Metabolomes in Mice.
Myostatin (gene symbol: Mstn) is an autocrine and paracrine inhibitor of muscle growth. Pregnant mice with genetically reduced levels of myostatin give birth to offspring with greater adult muscle mass and bone biomechanical strength. However, maternal myostatin is not detectable in fetal cir...
2023-06-08 | MTBLS3345 | MetaboLights
MetabolomicsSexual dimorphism in the fetal cardiac response to maternal nutrient restriction
Poor maternal nutrition causes intrauterine growth restriction (IUGR); however, its effects on fetal cardiac development are unclear. We have developed a baboon model of moderate maternal undernutrition, leading to IUGR. We hypothesized that the IUGR affects fetal cardiac structure and metabolism. S...
2018-04-30 | MTBLS426 | MetaboLights
MetabolomicsLipidomics of Near-Term Fetal and Newborn Sheep Cardiac Tissue (part-II)
Not available
ORGANISM(S): Ovis aries 
ST001061 | MetabolomicsWorkbench
MetabolomicsNMR Metabolomics of Near-Term Fetal and Newborn Sheep Cardiac Tissue (part-I)
Not available
ORGANISM(S): Ovis aries 
ST001060 | MetabolomicsWorkbench
MetabolomicsMetabolomic landscape of fetal organs development during late gestation in mice
Metabolism is the critical basis for mammalian physiological functions. The systematic metabolic characteristics of major organ development during late gestation to adapt to postnatal environmental changes are still absent. Here, we detected metabolic patterns of the mouse fetal organs, including th...
2025-08-23 | MTBLS12560 | MetaboLights
MetabolomicsNMR Metabolomics of Newborn Heart Tissue Exposed to Excess Maternal Cortisol in Late Gestation - Fetal (part -III)
Not available
ORGANISM(S): Ovis aries 
ST001108 | MetabolomicsWorkbench
MetabolomicsThe maturity in fetal pigs using a multi-fluid metabolomic approach
In mammalian species, the first days after birth are an important period for survival and the rates of mortality before weaning are high. In pigs, the perinatal deaths average 20% of the litter, with important economic and societal consequences. Among the factors influencing piglet survival at birth...
2020-07-07 | MTBLS1541 | MetaboLights
MetabolomicsLimited vertical transmission but profound immune dysregulation at the maternal-fetal interface after SARS-CoV-2 infection

The endemic of SARS-CoV-2 underscores the imperative to elucidate its effects on pregnancy, particularly regarding the potential for vertical transmission and its influence on the early maternal-fetal interface, which remain insufficiently defined. To address this, we performed an extensive cohor...

2026-03-05 | MTBLS13103 | MetaboLights
TranscriptomicsTissue-specific circular RNA induction during human fetal development
The pervasive expression of circular RNA from protein coding loci is a recently discovered feature of many eukaryotic gene expression programs. Computational methods to discover and quantify circular RNA are essential to the study of the mechanisms of circular RNA biogenesis and potential functiona...
ORGANISM(S): Homo sapiens 
2015-06-25 | E-GEOD-64283 | biostudies-arrayexpress
ProteomicsIn utero pulse-injection of isotopic amino acids quantifies protein turnover rates during murine fetal development
Protein translational control is a highly regulated step in the gene expression program during development and tools to quantify protein synthesis rates in a developing fetus are lacking. Here, we developed a novel in utero approach to quantify tissue-specific translational kinetics of the nascent p...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-04-30 | MSV000087342 | MassIVE
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