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MetabolomicsMetabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3, and BGLU4 in glycosylation of various flavonoids

Flavonoids are specialized metabolites that play important roles in plants, including interactions with the environment. The high structural diversity of this metabolite group is largely due to enzyme-mediated modifications of flavonoid core skeletons. In particular, glycosylation with different ...

2025-02-25 | MTBLS1965 | MetaboLights
MetabolomicsMass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism
Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with 50-80% patients exhibiting mutations in the von Hippel-Lindau (VHL) gene. RSUME (RWD domain (termed after three major RWD-containing proteins: RING finger-containing proteins, WD-repeat-containing proteins, and yeast DEAD (DEXD)...
2021-10-06 | MTBLS1935 | MetaboLights
MetabolomicsComprehensive quality standardization of Haizhixiaolin capsules via multi-component fingerprinting and metabolomic
Haizhixiaolin Capsule (HZXL), a traditional Chinese medicine hospital preparation for treating chronic prostatitis and urinary disorders, consists of ten herbal components. Due to the complexity of its multi-component nature, establishing a robust quality control system remains challenging. This stu...
2026-03-26 | MTBLS14148 | MetaboLights
MetabolomicsMetabolomic fingerprinting of bull spermatozoa for identification of fertility signature metabolites
The objective of the study was to identify the fertility-associated metabolites in bovine spermatozoa using liquid chromatography-mass spectrometry (LC-MS). Six Holstein Friesian crossbred bulls (three high-fertile and three low-fertile bulls) were the experimental animals. Sperm proteins were isola...
2021-12-07 | MTBLS1071 | MetaboLights
MetabolomicsFingerprinting gastrointestinal diseases by 1H NMR
Not available
ORGANISM(S): Homo sapiens 
ST001054 | MetabolomicsWorkbench
MetabolomicsMetabolomic and Metataxonomic Fingerprinting of Human Milk Suggests Compositional Stability over a Natural Term of Breastfeeding to 24 Months
Sparse data exist regarding the normal range of composition of maternal milk beyond the first postnatal weeks. This single timepoint, observational study in collaboration with the 'Parenting Science Gang' citizen science group evaluated the metabolite and bacterial composition of human milk from 62 ...
2022-02-11 | MTBLS1370 | MetaboLights
MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
MetabolomicsMetabolomic Fingerprinting of Human High Grade Serous Ovarian Carcinoma Cell Lines
Not available
ORGANISM(S): Homo sapiens 
ST001983 | MetabolomicsWorkbench
MetabolomicsEmploying fingerprinting of medicinal plants by means of LC-MS and machine learning for species identification task

A dataset of liquid chromatography-mass spectrometry measurements of medicinal plant extracts from 76 species was generated and used for training and validating plant species identification algorithms. Various strategies for data handling and feature space selection were tested. Constrained Tucke...

2022-04-15 | MTBLS688 | MetaboLights
MetabolomicsIntegrative multi-omics, HPLC fingerprinting and machine learning reveal distinct differences among three Dendrobium species from the Dabie Mountains
Dendrobium species are widely used in traditional Chinese medicine owing to their medicinal and nutritional value, yet the phytochemical diversity and molecular mechanisms underlying theirbioactivities remain poorly understood. To elucidate these traits, we performed an integrative multi-omics study...
2026-06-28 | MTBLS14876 | MetaboLights
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