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GenomicsHypoxic tumors are sensitive to FLASH radiotherapy
Hypoxic tumors are sensitive to FLASH radiotherapy
PRJNA926967 | ENA
UnknownFLASH Radiotherapy Enhances the Therapeutic Ratio in an Embryonic In Vivo Model of Pancreatic Carcinoma.
Not available
S-EPMC12635963 | biostudies-literature
GenomicsLocalized FLASH Radiotherapy Reduces Long-Term Skin and Muscle Damage While Preserving Systemic Homeostasis
Localized FLASH Radiotherapy Reduces Long-Term Skin and Muscle Damage While Preserving Systemic Homeostasis
PRJNA1322311 | ENA
TranscriptomicsLocalized FLASH Radiotherapy Reduces Long-Term Skin and Muscle Damage While Preserving Systemic Homeostasis
Radiotherapy (RT) is a cornerstone treatment for nearly 50% of cancer patients, yet its efficacy remains limited by cumulative damage to healthy tissues over time. Delivering RT at ultra-high dose rates (FLASH-RT) represents a transformative strategy, as it appears to maintain tumor control, while s...
ORGANISM(S): Mus musculus 
2025-09-15 | GSE307570 | GEO
GenomicsDifferential impact of FLASH and conventional radiotherapy on a pivotal metabolic organ: White Adipose Tissue
Differential impact of FLASH and conventional radiotherapy on a pivotal metabolic organ: White Adipose Tissue
PRJNA1447501 | ENA
TranscriptomicsHypoxic tumors are sensitive to FLASH radiotherapy
Purpose: Tumor hypoxia is a major cause of treatment resistance, especially to radiation therapy at conventional dose rate (CONV), and we wanted to assess whether hypoxia does alter tumor sensitivity to FLASH. Methods and materials: We engrafted several tumor types (glioblastoma [GBM], head and neck...
ORGANISM(S): Homo sapiens 
2024-01-24 | GSE223607 | GEO
GenomicsFLASH radiotherapy efficacy and toxicity
Evaluation of the late genotoxic effect of flash radiation therapy in mouse tissue
PRJEB86376 | ENA
UnknownPhenomenological insights into the FLASH radiotherapy-induced abscopal effect.
Not available
S-EPMC12486310 | biostudies-literature
TranscriptomicsSparing effects of FLASH irradiation in patient-derived lung tissue
This study aims to assess the effect of conventional radiotherapy compared to FLASH radiotherapy on healthy human lung tissue. FLASH radiotherapy, characterized by ultra-high dose rates, is hypothesized to spare healthy tissue from radiation-induced damage while maintaining efficacy against tumors. ...
ORGANISM(S): Homo sapiens 
2025-09-08 | GSE263484 | GEO
UnknownRadiobiological Aspects of FLASH Radiotherapy.
Not available
S-EPMC9599153 | biostudies-literature
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