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MetabolomicsFunctional metabolic molecules were identified as novel therapeutic targets to facilitate gemcitabine treatment against pancreatic cancer (Cells metabolomics)
Not available
ORGANISM(S): Homo sapiens 
ST002122 | MetabolomicsWorkbench
MetabolomicsFunctional metabolic molecules were identified as novel therapeutic targets to facilitate gemcitabine treatment against pancreatic cancer (Cells metabolomics with ATP)
Not available
ORGANISM(S): Homo sapiens 
ST002255 | MetabolomicsWorkbench
MetabolomicsFunctional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling

INTRODUCTION: Isoprenoids are amongst the most abundant and diverse biological molecules and are involved in a broad range of biological functions. Functional understanding of their biosynthesis is thus key in many fundamental and applicative fields, including systems biology, me...

2021-04-01 | MTBLS923 | MetaboLights
MetabolomicsFunctional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming
The axolotl (Ambystoma mexicanum) is a caudate amphibian, which has an extraordinary ability to restore a wide variety of damaged structures by a process denominated epimorphosis. While the origin and potentiality of progenitor cells that take part during epimorphic regeneration are known to ...
2021-11-04 | MTBLS1708 | MetaboLights
MetabolomicsMetabolic programming and functional remodeling by a c-di-GMP-centric hierarchy in aerobic granular sludge

This study systematically elucidates the hierarchical signaling regulatory network in aerobic granular sludge (AGS) by integrating dynamic analysis of quorum sensing signal molecules, microbial community structure profiling, and metabolomic characterization. The research reveals that c-di-GMP fun...

2025-12-10 | MTBLS13486 | MetaboLights
MetabolomicsMetabolomics-based and functional validation to explore the effect of the gut microbe-associated metabolite guanidinoacetic acid on rectal adenocarcinoma

Objective: The gut microbiota plays a crucial role in rectal adenocarcinoma (READ). Nonetheless, little is known about corresponding changes in gut microbiota–host interactions. This study aimed to identify the structure of the gut microbiota and the characteristics of faecal metabolites in patie...

2025-06-29 | MTBLS12620 | MetaboLights
GenomicsFunctional investigations of p53 acetylation enabled by heterobifunctional molecules
Functional investigations of p53 acetylation enabled by heterobifunctional molecules
PRJNA1158841 | ENA
GenomicsLong-term maintenance of functional primary human hepatocytes using small molecules
Long-term maintenance of functional primary human hepatocytes using small molecules
PRJNA557132 | ENA
GenomicsConversion of fibroblasts to functional Leydig like cells using defined small molecules
Conversion of fibroblasts to functional Leydig like cells using defined small molecules
PRJNA608265 | ENA
GenomicsGenome-wide maps of chromatin state during cardiac reprogramming of human fibroblasts by small molecules
Cardiomyocyte-like cells can be reprogrammed from somatic fibroblasts by overexpression of cardiac genes, providing a new avenue for cardiac regenerative therapy. Here we report an alternative approach in which functional cardiomyocytes can be rapidly and efficiently generated from human fibroblasts...
ORGANISM(S): Homo sapiens 
2016-02-19 | E-GEOD-78096 | biostudies-arrayexpress
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