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MetabolomicsIdentification of Biomarkers Using Metabolomics: From Chronic Non-Atrophic Gastritis and Chronic Atrophic Gastritis to Gastric Cancer

Gastric cancer (GC) is a severe malignancy characterized by late diagnosis, poor prognosis and low survival rates. Its progression is often linked to chronic non-atrophic gastritis (CNAG) and chronic atrophic gastritis (CAG), which show atypical symptoms. Identifying biomarkers for CNAG, CAG and ...

2026-09-29 | MTBLS12186 | MetaboLights
MetabolomicsNMR-based metabonomics and correlative analysis reveals potential bomarkers associated with chronic atrophic gastritis
Chronic atrophic gastritis (CAG) is one of the most important pre-cancerous states with a high prevalence. Exploring of the underlying mechanism and potential biomarkers is of significant importance for CAG. In the present work, 1H NMR-based metabonomics with correlative analysis was performed to an...
2016-08-31 | MTBLS340 | MetaboLights
TranscriptomicsResponse of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis
This SuperSeries is composed of the following subset Series: GSE16390: Response of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis 1 GSE16439: Response of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chroni...
ORGANISM(S): Mus musculus 
2009-10-26 | E-GEOD-16440 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MALT lymphoma and chronic gastritis tissue from the same patients
21 Tissue samples of gastric MALT lymphoma were compared by cDNA microarray studies with chronic gastritis tissues from the same patient. From each patient, multiple mucosal biopsies of the stomach were taken both from i) the macroscopically infiltrated area and ii) distant from the lymphoma. For co...
ORGANISM(S): Homo sapiens 
2007-07-24 | E-MEXP-1168 | biostudies-arrayexpress
TranscriptomicsResponse of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis 2
Helicobacter pylori infection is associated with development of gastric adenocarcinoma in a subset of infected humans, especially those that develop an antecedent condition, chronic atrophic gastritis (ChAG) characterized by loss of acid-producing parietal cells. Studies in a gnotobiotic transgenic ...
ORGANISM(S): Helicobacter pylori 
2010-06-20 | E-GEOD-16439 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis 1
Helicobacter pylori infection is associated with development of gastric adenocarcinoma in a subset of infected humans, especially those that develop an antecedent condition, chronic atrophic gastritis (ChAG) characterized by loss of acid-producing parietal cells. Studies in a gnotobiotic transgenic ...
ORGANISM(S): Mus musculus 
2009-11-11 | E-GEOD-16390 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile of human MALT lymphoma compared to gastritis and gDLBCL
To obtain global miRNA expression signatures of gDLBCL and its precursor lesions, total RNA isolated from 7-8 cases each of Helicobacter-associated reactive gastritis, low grade MALT lymphoma and high grade gDLBCL was hybridized to Agilent miRNA microarrays representing 795 human mature miRNAs. Unsu...
ORGANISM(S): Homo sapiens 
2010-10-02 | E-GEOD-24485 | biostudies-arrayexpress
TranscriptomicsmiRNA sequencing data from patients with non-active gastritis, chronic active gastritis and precursor lesions of gastric cancer.
Helicobacter pylori infection can induce gastric pathologies ranging from chronic gastritis to peptic ulcers and gastric cancer. Individuals´ response to H. pylori infection is complex and it depends on a combination of environmental factors, genetic background, host response and strain virulence. T...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-8890 | biostudies-arrayexpress
TranscriptomicsmRNA microarray data from patients with non-active gastritis, chronic active gastritis and precursor lesions of gastric cancer
Helicobacter pylori infection can induce gastric pathologies ranging from chronic gastritis to peptic ulcers and gastric cancer. Individuals´ response to H. pylori infection is complex and it depends on a combination of environmental factors, genetic background, host response and strain virulence. T...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-8889 | biostudies-arrayexpress
TranscriptomicsExpression data from Helicobacter pylori isolates infecting a gastric epithelial progenitor cell line
Helicobacter pylori clinical isolates can establish themselves in gastric epithelial stem cells and this interaction may have implications for gastric tumorigenesis. Mouse gastric epithelial progenitor cells (mGEPs) were infected for 24hrs with Helicobacter pylori clinical isolates Kx1 and Kx2. Kx1 ...
ORGANISM(S): Helicobacter pylori 
2010-05-26 | E-GEOD-10261 | biostudies-arrayexpress
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