Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse colonic goblet cells deficient in Atg5
Purpose of this experiment was to gain insight into the transcriptional changes resulting from Atg5 deficiency in colonic goblet cells.
ORGANISM(S): Mus musculus 
2010-09-30 | E-TABM-815 | biostudies-arrayexpress
ProteomicsTrans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation
A key feature in intestinal immunity is the dynamic intestinal barrier, which separates the host from resident and pathogenic microbiota through a mucus gel impregnated with antimicrobial peptides. The mechanisms underlying the maintenance and function of this intestinal barrier are not completely ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-12-12 | MSV000090883 | MassIVE
ProteomicsIdentification of key pro-survival proteins in the isolated colonic goblet cells of Winnie, a murine model of spontaneous colitis
A proteomics comparison of goblet cell extracts prepared from control mice and animals expressing a misfolding mutant of Muc2, the major secretory product of goblet cells.
ORGANISM(S): Mus musculus (Mouse) 
2019-09-26 | PXD013166 | Pride
Quantitative proteomics  apoptosis  er stress  proliferation  ulcerative colitis  cancer 
TranscriptomicsTranscription profiling of mouse allergen-induced goblet cells
High numbers of goblet cells in airways contribute to the mucus obstruction characteristic of asthmatic airways. Allergen challenged mice exhibit robust expression of goblet cells within airway surface epithelium. This study looks at the temporal analysis of IL-13 exposed murine airways to elucida...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-481 | biostudies-arrayexpress
TranscriptomicsGene expression in small intestinal and colonic goblet cells from C57Bl/6 mice
Microarray analysis of goblet cells isolated from the small intestine or colon was completed to compare the cells between the two parts of the intestine. Total epithelium was isolated from the intestine by incubation in HBSS+0.05% EDTA at 37 C for 15 minutes. Goblet cells were isolated by FACS sorti...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-52418 | biostudies-arrayexpress
ProteomicsIleum and colon goblet cell proteome
This study is a comparative proteomics study of FACS sorted Muc2 expressing and non expressing cells in mouse ileum and colon.
ORGANISM(S): Mus musculus (Mouse) 
2021-04-19 | PXD011527 | Pride
Ileum Proteomics Goblet cells Colon 
GenomicsGene expression changes induced by zinc deficiency in intestinal goblet cells
Gene expression changes induced by zinc deficiency in intestinal goblet cells
PRJNA1423241 | ENA
TranscriptomicsComparison of Cancer-Associated Genetic Abnormalities in Columnar-Lined Esophagus with and without Goblet Cells
The requirement of goblet cells (intestinal metaplasia; IM) to define BarrettM-bM-^@M-^Ys esophagus (BE) remains controversial as some studies have shown that the risk of progression to esophageal adenocarcinoma (EAC) is similar for non-goblet cell metaplasia (NGM) and IM. IM harbors genomic aberrat...
ORGANISM(S): Homo sapiens 
2012-12-15 | E-GEOD-40769 | biostudies-arrayexpress
ProteomicsCathelicidin deficiency disrupts goblet cell mucus secretion but not mucus associated proteins in Citrobacter rodentium-induced colitis
Colonic goblet cells respond to invading enteropathogens by secreting Muc2 mucin and other specific goblet cell proteins that physically entrap and expel microbes away from the epithelium. At present, it is unclear how innate effectors in the gut, including small cationic cathelicidin peptides secre...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-04 | PXD041957 | Pride
Colonic epithelium  cathelicidin  goblet cells  mucus  citrobacter rodentium  reactive oxygen species 
GenomicsGene expression profile of colonic goblet cells (GCs) from SpdefKO_RedMUC298trTg and RedMUC298trTg mice
Gene expression profile of colonic goblet cells (GCs) from SpdefKO_RedMUC298trTg and RedMUC298trTg mice
PRJNA664463 | ENA
Sort   by:  
 Page size