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ProteomicsThanatin Targets the Inter-Membrane Protein Complex Required for Lipopolysaccharide Transport in Escherichia coli
With the increasing resistance of many Gram-negative bacteria to existing classes of antibiotics, identifying new paradigms in antimicrobial discovery is an important research priority. Of special interest here are the proteins required for the biogenesis of the symmetric Gram-negative bacterial out...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2020-02-04 | MSV000084897 | MassIVE
MetabolomicsExploring the effect of estrogen on Candida albicans hyphal cell wall glycans and ergosterol synthesis
Increased levels of 17-β estradiol (E2) due to pregnancy in young women or to hormonal replacement therapy in postmenopausal women have long been associated with an increased risk of yeast infections. Nevertheless, the effect underlying the role of E2 in Candida albicans infections is not wel...
2025-09-11 | MTBLS5821 | MetaboLights
UnknownCell envelope growth of Gram-negative bacteria proceeds independently of cell wall synthesis.
Not available
S-EPMC10350831 | biostudies-literature
TranscriptomicsGene expression response to bacterial phagocytosis by S2 cells (control and eater RNAi knock down)
The Drosophila phagocytic receptor Eater is expressed specifically in phagocytic hemocytes. It contributes to host immune defense and is required for survival of bacterial infections. Eater is involved in recognition and phagocytosis of bacteria. We used microarrays to determine whether any gene exp...
ORGANISM(S): Drosophila melanogaster 
2011-08-24 | E-GEOD-31564 | biostudies-arrayexpress
UnknownDisruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway.
Not available
S-EPMC4801249 | biostudies-literature
ProteomicsFilamentous growth, cell envelope architecture and surface appendages in Litorilinea aerophila
Litorilinea aerophila, a filamentous member of the phylum Chloroflexota (class Caldilineae), exhibits unique morphological and cell envelope features that challenge traditional bacterial models. Although historically described as Gram-negative, Chloroflexota are increasingly considered as monoderm, ...
ORGANISM(S): Litorilinea aerophila Bacteria 
2026-06-09 | PXD066799 | Pride
Cell surface structures Cell envelope Chloroflexota Lc-ms/ms 
UnknownA Dynamic Network of Proteins Facilitate Cell Envelope Biogenesis in Gram-Negative Bacteria.
Not available
S-EPMC8657477 | biostudies-literature
MetabolomicsNitrate Reductase NarGHJI Modulates Vancomycin Susceptibility by Coordinating Cell Wall Remodeling and Agmatine Metabolism in Staphylococcus aureus
Staphylococcus aureus is a ubiquitous pathogen responsible for a wide range of severe infections. Our previous work established that the nitrate reductase NarGHJI modulates bacterial pathogenicity through regulation of the agr system, yet its role in antibiotic resistance remains poorly understood. ...
2026-07-07 | MTBLS14968 | MetaboLights
ProteomicsDisulfide bonds are critical for stabilizing cell division, cell envelope biogenesis, and antibiotic resistance proteins in mycobacteria
Mycobacterium, including Mycobacterium tuberculosis, the etiological agent of tuberculosis, have a unique cell envelope critical for their survival and antibacterial resistance. The cell envelope's assembly and maintenance influence permeability, making it a key target against multidrug resistant st...
ORGANISM(S): Mycobacterium Smegmatis Str. Mc2 155 (ncbitaxon:246196) 
2025-01-16 | MSV000096877 | MassIVE
UnknownDetection of antimicrobial impact on gram-negative bacterial cell envelope based on single-cell imaging by scanning electron microscopy.
Not available
S-EPMC10338463 | biostudies-literature
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