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ProteomicsCharacterisation of BiP-GRP94-HT2 interaction
Characterization of the interaction of BiP-GRP94 in the presence and absence of HT2 using cross linking with DSBU and subsequent analysis of cross linked peptides by LC-MS/MS
ORGANISM(S): Mus musculus (Mouse) 
2025-07-14 | PXD059917 | Pride
Bip  grp94  cross linking ms  cl-ms  dsbu 
GenomicsEffect of knockdown of GRP94 on gene expression of MKN-45 cells
Effect of knockdown of GRP94 on gene expression of MKN-45 cells
PRJNA1113161 | ENA
TranscriptomicsAI662270-GRP94 axis couples the unfolded protein response to mitochondrial dynamics during acute myocardial infarction
Endoplasmic reticulum stress (ERS) response, triggered by myocardial ischemia, contributes to cardiac injury through unresolved mechanisms. Our study reveals that the chaperone GRP94 attenuates mitochondrial fragmentation and ischemic damage by inhibiting OPA1 hydrolysis to S-OPA1 post-acute myocard...
ORGANISM(S): Mus musculus 
2025-08-13 | GSE304427 | GEO
GenomicsAI662270-GRP94 axis couples the unfolded protein response to mitochondrial dynamics during acute myocardial infarction
AI662270-GRP94 axis couples the unfolded protein response to mitochondrial dynamics during acute myocardial infarction
PRJNA1301289 | ENA
TranscriptomicsEffect of knockdown of GRP94 on gene expression of MKN-45 cells
Anoikis resistance allows cancer cells to avoid death caused by detachment from the extracellular matrix's adhesion, enabling these cells to infiltrate and migrate to regions such as the peritoneum.Glucose-regulated protein 94 (GRP94, alternatively labeled as HSP90B1) is typically stress-induced and...
ORGANISM(S): Homo sapiens 
2024-07-25 | GSE267811 | GEO
UnknownResorcinol-Based Grp94-Selective Inhibitors.
Not available
S-EPMC5641966 | biostudies-literature
UnknownConformationally Restricted Grp94-Selective Inhibitors.
Not available
S-EPMC11740130 | biostudies-literature
UnknownStructural transitions modulate the chaperone activities of Grp94.
Not available
S-EPMC10962938 | biostudies-literature
UnknownDevelopment of a Grp94 inhibitor.
Not available
S-EPMC3414055 | biostudies-literature
UnknownStructure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding.
Not available
S-EPMC5897183 | biostudies-literature
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