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MetabolomicsMicrobial-derived Hyodeoxycholic Acid Ameliorates Painful Diabetic Neuropathy by Modulating Dorsal Root Ganglion TLR4-Mediated Neuroinflammation Signaling Pathway

BACKGROUND: Painful diabetic neuropathy (PDN) is characterized by hyperalgesia and neuronal hyperexcitability. Although gut microbiota dysbiosis have been found in PDN, how microbiota influences PDN remains largely unexplored. RESULTS: Gut microbiota and its metabolites impacted PDN was investiga...

2026-08-24 | MTBLS12087 | MetaboLights
GenomicsHereditary sensory and autonomic neuropathy in a family of mixed breed dogs
Hereditary sensory and autonomic neuropathy in a family of mixed breed dogs is associated with a novel FAM134B (RETREG1) mutation
PRJEB39868 | ENA
ProteomicsMitochondrial energetic failure underlies FLVCR1-related sensory neuropathy
Genetic pain loss disorders represent a heterogeneous group of rare diseases mainly characterized by defective nociception. Understanding the underlying molecular mechanism is fundamental to improve the treatment of patients affected by these rare disorders. Feline Leukemia Virus Subgroup C Receptor...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD071580 | Pride
Posterior column ataxia and retinitis pigmentosa  pcarp  retinitis pigmentosa  hereditary sensory and autonomic neuropathy  hsan  heme  choline  mams  mercs 
UnknownBlended phenotype of TECPR2-associated hereditary sensory-autonomic neuropathy and Temple syndrome.
Not available
S-EPMC11822794 | biostudies-literature
UnknownMutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I.
Not available
S-EPMC2948807 | biostudies-literature
UnknownHereditary Sensory and Autonomic Neuropathy Type 2: A Case Report and a Review of the Literature.
Not available
S-EPMC12650649 | biostudies-literature
UnknownDe novo pathogenic DNM1L variant in a patient diagnosed with atypical hereditary sensory and autonomic neuropathy.
Not available
S-EPMC6785439 | biostudies-literature
UnknownFrequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort.
Not available
S-EPMC3752368 | biostudies-literature
UnknownHereditary sensory and autonomic neuropathy type V: Report of a rare case.
Not available
S-EPMC4319325 | biostudies-literature
UnknownHereditary sensory neuropathy type I.
Not available
S-EPMC2311280 | biostudies-literature
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