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Analyses of Resected Human Brain Metastases of Breast Cancer Reveal the Association between Up-Regulation of Hexokinase 2 and Poor Prognosis. Brain metastases of breast cancer seem to be increasing in incidence as systemic therapy improves. Metastatic disease in the brain is associated with high mor...
ORGANISM(S): Homo sapiens 
The Aryl Hydrocarbon Receptor (AHR) regulates the expression of numerous genes in response to activation by agonists including xenobiotics. Although it is well appreciated that environmental signals and cell intrinsic features may modulate this transcriptional response, how it is mechanistically ach...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD028992 | Pride
Circulating tumor cells (CTCs) represent the molecular characteristics of tumor sites and travel in the blood for seeding distant metastases. "EpCAM+/pan-cytokeratin (CK)+/CD45-/DAPI+" has been widely accepted as a CTC definition, especially in breast cancer, prostate cancer and colorectal cancer. H...
ORGANISM(S): Homo sapiens 
Hexokinase 2 and lactate
The present phosphorylation-modified proteome detected hexokinase 2-dependent phosphosites
ORGANISM(S): Mus Musculus 
2025-02-07 | PXD060592 |
MicroRNAs (miRNAs) have emerged as important gene regulators and are recognized as key players in tumorigenesis. miR-143 is reported to be down-regulated in several cancers, but knowledge of its targets in colon cancer remains limited. To investigate the role of miR-143 in colon cancer, we have empl...
ORGANISM(S): Homo sapiens 
Hexokinase 2 is dispensable for T cell-dependent immunity
Hexokinase 2 detects cytokeratin negative circulating tumor cells in lung adenocarcinoma
NOVEL HEXOKINASE-2 ASSOCIATED INFLAMMATORY PROCESSES IN THE GLIOBLASTOMA TUMOUR MICROENVIRONMENT
It has been strongly argued that plant cells should have a means of sensing sugars at the cell surface, so that extracellular and intracellular sugars can be sensed separately and their metabolism coordinated (Lalonde et al., Plant Cell, 11, 707-26, 2000). There is good evidence for an intracellular...
ORGANISM(S): Arabidopsis thaliana 
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