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ProteomicsIntegrated Proteomic and Metabolomic Analysis of Muscle Atrophy Induced by Hindlimb Unloading
Skeletal muscle atrophy, which is induced by factors such as disuse, spaceflight, certain medications, neurological disorders, and malnutrition, is a global health issue lacking effective treatment. Hindlimb unloading is a commonly used model for muscle atrophy. However, the underlying mechanism of ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-07 | PXD057671 | Pride
Muscle atrophy  hindlimb unloading  proteomics  metabolomics  integrated analysis 
TranscriptomicsMicroRNA expression in rat soleus muscle during atrophy induced by hindlimb suspension
The objective of the study was to identify microRNAs expressed in the rat soleus muscle and determine if their expression was changed in response to hindlimb suspension. The microRNA expression profile (Sanger miRBase 9.0) of the rat soleus muscle was determined in the following three groups: contro...
ORGANISM(S): Rattus norvegicus 
2009-08-25 | E-GEOD-17776 | biostudies-arrayexpress
ProteomicsMouse hippocampal tissue subjected to 7-Days and 28-Days hindlimb unloading and control group
Mouse hippocampal tissue subjected to 7-Days and 28-Days hindlimb unloading and control group
ORGANISM(S): Mus Musculus 
2025-06-17 | PXD065089 |
GenomicsAnalysis of skeletal muscle gene expression upon mouse hindlimb unloading and reloading
Analysis of skeletal muscle gene expression upon mouse hindlimb unloading and reloading
PRJNA993705 | ENA
GenomicsTranscriptome of bone marrow cells from mice with osteoporosis induced bu hindlimb unloading
Transcriptome of bone marrow cells from mice with osteoporosis induced bu hindlimb unloading
PRJNA1182730 | ENA
ProteomicsMouse hippocampal tissue isolated synaptic fractions from mice subjected to 7-Days and 28-Days hindlimb unloading and control group
Mouse hippocampal tissue isolated synaptic fractions from mice subjected to 7-Days and 28-Days hindlimb unloading and control group
ORGANISM(S): Mus Musculus 
2025-06-17 | PXD065084 |
ProteomicsEmploying Hindlimb Unloading Model for The Identification of Serum Biomarkers Associated with Cardiovascular and Skeletal Muscle Deconditioning.
Microgravity and prolonged periods of inactivity cause a variety of diseases, including skeletal muscle mass loss and weakening as well as cardiovascular deconditioning. The primary causes of the inadequate preventative measures for these deconditionings are the lack of biomarkers and unknown underl...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD042753 | Pride
Mouse Plasma Skeletal muscle atrophy Recovery 
TranscriptomicsMuscle unloading and reloading
Examination of effect of mechanical loading induced by hindlimb suspension, and subsequent reloading, in soleus muscle in 14 day old female pathogen–free Wistar rats. Keywords = skeletal muscle Keywords = atrophy
ORGANISM(S): Rattus norvegicus 
2010-06-05 | E-GEOD-673 | biostudies-arrayexpress
TranscriptomicsHindlimb suspension and reloading study
Analysis of effect of hindlimb suspension and reloading on C57Bl/6 mouse soleus muscle. Experimental groups examined: -Control mice, 14 days -Hindlimb suspension for 7 days -Hindlimb suspension for 7 days, and subsequent reloading for 1 day -Hindlimb suspension for 7 days, and subsequent reloading ...
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-1293 | biostudies-arrayexpress
TranscriptomicsGene expression changes in femur bone induced by skeletal muscle unloading
Gene expression changes in femur bone induced by acute skeletal muscle unloading, which leads to physiological changes including muscle atrophy, weakness and results in bone remodelling and subsequent loss of bone mass, was investigated by hind-limb suspension (HLS) treatment of Male ICR mice (28–32...
ORGANISM(S): Mus musculus 
2010-12-21 | E-GEOD-11933 | biostudies-arrayexpress
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