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MetabolomicsVirus-induced codon-specific reprogramming to favor viral RNA translation
Recent evidence indicates that codon usage bias regulates gene expression. How viruses, such as the emerging mosquito-borne Chikungunya virus (CHIKV), express their genomes at high levels despite an enrichment in rare codons remains a puzzling question. Using ribosome footprinting, here we analysed ...
2025-06-16 | MTBLS2443 | MetaboLights
ProteomicsMegavirus Translation Initiation Factor 4A Plays an Important Role in the Regulation of Viral and Host Protein Translation and Host Adaptation
The presence of translation-related proteins has long been seen as a critical distinction between viruses and cellular life, the discovery of giant viruses has challenged this standard. We prove that the potential eukaryotic translation initiation factor 4A (eIF4A, Mb0671) encoded by the Megavirus b...
ORGANISM(S): Mimivirus Sp. Sh 
2024-10-03 | PXD056594 |
ProteomicsAfrican swine fever virus ubiquitinconjugating enzyme interacts with host translation machinery to regulate the host protein synthesis
African Swine Fever virus (ASFV) causes one of the most relevant emerging diseases affecting swine, now extended through three continents. The virus has a large coding capacity to deploy an arsenal of molecules antagonizing the host functions. In the present work, we have studied the only known E2 v...
ORGANISM(S): Homo sapiens (Human) 
2020-12-14 | PXD023086 | Pride
Asfv  ubiquitin conjugating enzyme  host translation 
MetabolomicsA gut-associated Prevotellaceae_NK3B31_group lineage modulates host metabolic pathways and enhances feed efficiency in ducks

Amidst the mismatch between domestic feed supply and demand in China, along with the competition for food between humans and animals, optimizing feed efficiency has become crucial for industry growth. Nevertheless, the biological processes driving variations in feed efficiency remain unexplored. ...

2026-03-10 | MTBLS14017 | MetaboLights
MetabolomicsA gut-associated Prevotellaceae_NK3B31_group lineage modulates host metabolic pathways and enhances feed efficiency in ducks

Amidst the mismatch between domestic feed supply and demand in China, along with the competition for food between humans and animals, optimizing feed efficiency has become crucial for industry growth. Nevertheless, the biological processes driving variations in feed efficiency remain unexplored. ...

2026-03-10 | MTBLS14009 | MetaboLights
MetabolomicsA gut-associated Prevotellaceae_NK3B31_group lineage modulates host metabolic pathways and enhances feed efficiency in ducks

Amidst the mismatch between domestic feed supply and demand in China, along with the competition for food between humans and animals, optimizing feed efficiency has become crucial for industry growth. Nevertheless, the biological processes driving variations in feed efficiency remain unexplored. ...

2026-03-10 | MTBLS14013 | MetaboLights
ProteomicsRibosome quality control activity potentiates vaccinia virus protein synthesis during infection
Ribosomes are highly abundant cellular machines that perform the essential task of translating the genetic code into proteins. Cellular translation activity is finely tuned and proteostasis insults, such as those incurred upon viral infection, activate stress signaling pathways that result in transl...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Vaccinia Virus Wr (ncbitaxon:10254) 
2021-01-05 | MSV000086660 | MassIVE
TranscriptomicsThe Relationship between Virus Replication and Host Gene Expression in Lymphatic Tissue during HIV-1 Infection
During HIV-1 infection, there is a massive perturbation of host gene expression, but as yet, genome-wide studies have not identified host genes affecting HIV-1 replication in lymphatic tissue, the primary site of virus-host interactions. In this study, we isolated RNA from the inguinal lymph nodes ...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-21589 | biostudies-arrayexpress
ProteomicsValidation of detected viral and host peptides from COVID-19 nasopharyngeal swab samples
In the current scenario of COVID-19, an assay that can efficiently and specifically detect infection by SARS-COV2 is required. Nasopharyngeal swabs are non-invasive samples and can be conveniently acquired from the population to be screened. In this work, we have validated a few viral and host pepti...
ORGANISM(S): Homo Sapiens Severe Acute Respiratory Syndrome Coronavirus 2 
PXD021845 | panorama
GenomicsRespiratory syncytial virus (RSV) enhances translation of virus-resembling AU-rich host transcripts
Respiratory syncytial virus (RSV) enhances translation of virus-resembling AU-rich host transcripts
PRJNA1118414 | ENA
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