Sort   by:  
 Page size 
ProteomicsThe long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
Glioblastoma is the most common malignant primary brain tumor. Clinically relevant biomarkers are restricted to isocitrate dehydrogenase (IDH) gene 1 or 2 mutation and O6-methylguanine DNA methyltransferase (MGMT) promoter methylation. Long non-coding RNA (lncRNA) alterations may contribute to gliob...
ORGANISM(S): Homo sapiens (Human) 
2022-01-19 | PXD020141 | Pride
Glioblastoma  hotairm1  long non-coding rna  radiosensitivity 
GenomicsHOTAIRM1 knockdown microarray
HOTAIRM1 knockdown microarray
PRJNA792423 | ENA
ProteomicslncRNA HOTAIRM1 Coordinates with RNA Processing Factors in DNA Damage Repair
The eukaryotic RNA processing factor Y14 participates in double-strand break (DSB) repair via its RNA-dependent interaction with the non-homologous end-joining (NHEJ) complex. We identified the long non-coding RNA HOTAIRM1 as a candidate that mediates this interaction. HOTAIRM1 localized to DNA dama...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD034470 | Pride
Lc/ms/ms based proteomics 
TranscriptomicsHOTAIRM1 knockdown microarray
To investigate the target genes of HOTAIRM1 in glioma cells, we conducted a lncRNA + mRNA expression microarray analysis to identify novel HOTAIRM1 regulating genes. Three glioma cell lines U87MG, T98G and A172 stably knockdown HOTAIRM1 were used as the experiments models. We conservatively establis...
ORGANISM(S): Homo sapiens 
2021-12-26 | GSE192627 | GEO
GenomicsRNA-seq comparative analysis of HOTAIRM1 knockdown in Caki-1 cells
RNA-seq comparative analysis of HOTAIRM1 knockdown in Caki-1 cells
PRJNA562846 | ENA
GenomicsThe long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
PRJNA638410 | ENA
TranscriptomicsThe long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
Glioblastoma is the most common malignant primary brain tumor. Clinically relevant biomarkers are restricted to isocitrate dehydrogenase (IDH) gene 1 or 2 mutation and O6-methylguanine DNA methyltransferase (MGMT) promoter methylation. Long non-coding RNA (lncRNA) alterations may contribute to gliob...
ORGANISM(S): Homo sapiens 
2020-06-10 | GSE152147 | GEO
TranscriptomicsHOTAIRM1 suppresses Estrogen Receptor activity in breast cancer by restricting chromatin accessibility of pioneer factor FOXA1
Although a majority of breast cancers (BrCa) are Estrogen receptor-alpha (ERa)-positive, existing endocrine therapies that target ERa can lead to hormone-resistant disease. The mechanisms of how normal breast epithelium is transformed into malignant remain poorly defined, and a deeper understanding ...
ORGANISM(S): Homo sapiens 
2023-08-15 | GSE135894 | GEO
GenomicsHOTAIRM1 suppresses Estrogen Receptor activity in breast cancer by restricting chromatin accessibility of pioneer factor FOXA1
HOTAIRM1 suppresses Estrogen Receptor activity in breast cancer by restricting chromatin accessibility of pioneer factor FOXA1
PRJNA560493 | ENA
UnknownUpregulation of HOTAIRM1 increases migration and invasion by glioblastoma cells.
Not available
S-EPMC7880397 | biostudies-literature
Sort   by:  
 Page size