hspc - OmicsDI

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Unknown (981)
Genomics (825)
Transcriptomics (530)
Other (46)
Proteomics (36)
Methylation profiling (8)
Metabolomics (2)

Organisms

Homo sapiens (354)
Mus musculus (300)
Danio rerio (43)
Bombyx mori (28)
Klebsiella pneumoniae (28)
Schizosaccharomyces pombe (28)
Streptomyces coelicolor A3(2) (28)
Human immunodeficiency virus 1 (28)
Oryza sativa Indica Group (28)
Sinorhizobium meliloti BL225C (28)
Vitis (28)
Sus scrofa domesticus (28)
Ostreococcus tauri (28)
Saccharomyces cerevisiae (28)
Synechocystis sp. PCC 6803 (28)
Olavius algarvensis Gamma 1 endosymbiont (28)
Candida albicans (5)
Drosophila melanogaster (5)
Arabidopsis thaliana (4)
Macaca mulatta (4)
Heterocephalus glaber (4)
Saccharomyces cerevisiae (3)
synthetic construct (3)
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Austrofundulus limnaeus (1)
Caenorhabditis elegans (1)
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Escherichia coli (1)
Mus (1)

Organisms

Homo sapiens (290)
Mus musculus (261)
Danio rerio (45)
Heterocephalus glaber (3)
Macaca mulatta (3)
Drosophila melanogaster (2)
Pan troglodytes (1)
Mus (1)
Canis lupus familiaris (1)
mouse gut metagenome (1)
unidentified (1)
synthetic construct (1)

Repository

ENA (695)
geo (546)
biostudies-arrayexpress (136)
EGA (30)
pride (28)
MassIVE (5)
iProX (3)
MetaboLights (2)
ExpressionAtlas (1)
NODE (1)

Tissue

Bone marrow (7)
Cell culture (5)
Blood (4)
Stem cell (3)
Blood cell (3)
CD34+HSPC-Derived Erythroid cells (1)
Preterm umbilical cord blood (1)
HESC-Derived Erythroid cells (1)
Fetal liver (1)
Yolk sac (1)
Umbilical cord blood (1)
Hematopoietic progenitor cell antigen CD34 (human) (1)
Hematopoietic precursor cell (1)
Granulocyte (1)
Common myeloid progenitor (1)
Hematopoietic stem cell (1)
Trophozoite (1)
Extracellular exosome (1)
Mesenchymal stem cell of the bone marrow (1)
Mesenchymal cell (1)
Leukocyte (1)
Brain (1)
Blood plasma (1)
Spleen (1)
Primary cell (1)
Erythrocyte (1)
Epithelial cell (1)
Neutrophil (1)
T cell (1)

Disease

Myelodysplastic syndrome (2)
Acute leukemia (2)
Cancer (1)
Hematopoietic system (1)
Myelofibrosis (1)
Essential thrombocythemia (1)
Polycythemia vera (1)
Myeloid leukemia (1)
Bone marrow (1)
Pre-eclampsia (1)
Prostate adenocarcinoma (1)
Chronic myeloid leukemia (1)
Giardiasis (1)
Myeloproliferative neoplasm (1)
Disease free (1)

Technology Type

Mass Spectrometry (28)
Shotgun proteomics (14)
Bottom-up proteomics (9)
SWATH MS (5)
Mass spectrometry assay (2)
Data-independent acquisition (1)
Data-dependent acquisition (1)
Affinity purification coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (14)
NextSeq 500 (5)
Flow Cytometer (3)
NA (3)
NextSeq 550 (3)
Thermomixer (2)
Illumina HiSeq 2000 (2)
Liquid Chromatography MS - positive - reverse-phase (2)
Liquid Chromatography MS - negative - reverse-phase (2)
N/C (1)
NextSeq 500, 75 bp single end lane (1)
BD Rhapsody Express Instrument (1)
Real-time PCR Thermal Cycler (1)
Illumina Genome Analyzer II (1)
Illumina NovaSeq X (1)
Illumina HiSeq 1000 (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 3000 (1)
Oribtrap Velos Fusion (1)
SolariX (1)
Orbitrap Fusion (1)
Q Exactive Plus (1)
Orbitrap Fusion Lumos (1)

Publication Date

2025 (105)
2024 (85)
2023 (78)
2026 (64)
2022 (56)
2016 (46)
2021 (42)
2019 (40)
2020 (33)
2012 (30)
2015 (29)
2013 (24)
2014 (22)
2018 (19)
2011 (16)
2017 (14)
2010 (8)
2009 (3)
2008 (3)
2007 (1)
2005 (1)

CHEBI ID

CHEBI:140947 (1)

Metabolite Name

N-(3-bromophenyl)-2-[4-(morpholin-4-ylcarbonyl)-2-oxohydroquinolyl]acetamide (1)
1,2,4-Triazin-5(2H)-one, 6-(1,1-dimethylethyl)-3-(methylthio)- (1)
2-Hydroxy-4-Methoxychalcone (1)
N,N-Diethyl-4-Hydroxybenzamide (1)
P-Toluenesulfonamide (1)
2-(methylethylidene)butanedioic acid (1)
2-(3-(8-hydroxyoctyl)phenoxy)-2-methylpropanoic acid (1)
2-(4-methyl-6-(2-naphthyloxy)pyrimidin-2-ylthio)-1-phenylethan-1-one (1)
PS(18:1/18:0) (1)
2-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazol-5-yl)-4-ethyl-5-methoxyphenol (1)
3,4-dimethyl-9-phenyl-7H-furo[2,3-f]chromen-7-one (1)
12-Hydroxy-6-Epi-Albrassitriol (1)
Ethyl 2-[2-(1,3,7-trimethyl-2,6-dioxo-1,3,7-trihydropurin-8-ylthio)benzimidazo lyl]acetate (1)
[4-(difluoromethoxy)-3-ethoxyphenyl]-N-(1-methylpyrazol-3-yl)carboxamide (1)
2-{4-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)prop-1-enyl]phenoxy}acetamide (1)
Sissotrine (1)
Methyl 2-[(5,6,7-trimethoxy-3-oxohydroisobenzofuran-4-yl)methylthio]benzoate (1)
N-(2-chlorophenyl)-2-[2-oxo-4-(piperidylcarbonyl)hydroquinolyl]acetamide (1)
NA-135 (1)
1,3,6-Trihydroxy-2-(3-methylbut-2-enyl)xanthen-9-one (1)
7-(1,6-dihydroxy-3-methyl-5-(methylethyl)-8-{[(2-methylphenyl)amino]methylene} -7-oxo(2-naphthyl))-3,8-dihydroxy-6-methyl-4-(methylethyl)-1-{[(2-methylphenyl )amino]methylene}naphthalen-2-one (1)
Phenylmethyl 1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]pyrrolidine-2-carboxylate (1)
7-Benzofurancarboxylic acid, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-4-methoxy-6-(2-phenylethyl)- (1)
3-ethyl-4-hydroxy-1-benzylhydroquinolin-2-one (1)
Kaurenic acid (1)
(2Z)-2-benzoxazol-2-yl-3-(4-hydroxy-3-methoxyphenyl)-1-(4-methylphenyl)prop-2- en-1-one (1)
2-[4-(N,N-diethylcarbamoyl)-2-oxohydroquinolyl]-N-(2,4-difluorophenyl)acetamid e (1)
Pantothenic acid (Not validated) (1)
2H-benzo[3,4-d]1,3-dioxolen-5-yl-N-(4,5,6,7-tetrahydrobenzothiazol-2-yl)carbox amide (1)
1H-indole-3-carboxamide (1)

First Public Date

2025 (121)
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2021 (50)
2019 (48)
2014 (39)
2020 (38)
2018 (23)
2016 (17)
2017 (15)
2015 (15)
2013 (3)

Study type

Transcription profiling by array (75)
RNA-seq of coding RNA (21)
ChIP-seq (7)
RNA-seq of coding RNA from single cells (7)
Other (3)
ChIP-chip by tiling array (2)
ATAC-seq (2)
DNA-seq (2)
Methylation profiling by array (2)
Methylation profiling by high throughput sequencing (2)
RNA-seq of non coding RNA (2)
Transcription profiling by SAGE (1)
Baseline (1)
Differential (1)
Animal - One-color microarray (1)
MicroRNA profiling by high-throughput sequencing (1)
Animal - Single-cell sequencing (1)
Human - Single-cell sequencing (1)
Transcription profiling by RT-PCR (1)
Comparative genomic hybridization by array (1)
RIP-seq (1)
ScATAC-seq (1)

Release Date

2021 (124)
2023 (109)
2022 (101)
2025 (99)
2024 (90)
2020 (78)
2016 (78)
2019 (73)
2018 (72)
2015 (69)
2017 (52)
2014 (38)
2012 (34)
2013 (32)
2026 (24)
2011 (15)
2010 (14)
2009 (8)
2008 (3)
2005 (2)
2007 (1)
2004 (1)

Lab affiliation

Department of Biochemistry, Indian Institute of Science, Bangalore - 560 012 India (1)
Division of Obstetrics and Gynecology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden (1)
Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, the Netherlands. (1)
Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands (1)
UK Dementia Research Institute University of Dundee (1)
School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Korea (1)
Head, Division of Protective Immunity Children’s Hospital of Philadelphia 816F ARC, 3615 Civic Center Blvd Philadelphia, PA 19104 (1)
Hoflack Lab (1)
1 Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada 2 Department of Molecular Genetics, University of Toronto, Toronto, ON M5S1A5, Canada (1)
San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy (1)
Committee on Cancer Biology, The University of Chicago, Chicago, IL, USA Department of Pathology, The University of Chicago, Chicago, IL, USA Department of Pediatrics, The University of Chicago, Chicago, IL, USA The University of Chicago Medicine Comprehensive Cancer Center, University of Chicago, Chicago, IL, USA (1)
Professor of Pediatrics Children’s Hospital of Philadelphia 3615 Civic Center Blvd Philadelphia, PA 19104 (1)
Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, Lund, Sweden (1)
Children’s Hospital of Philadelphia 3615 Civic Center Blvd. Philadelphia, PA 19104 (1)
Department of Medical Oncology and Hematology, University and University Hospital Zurich, Zurich, Switzerland Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland (1)
UK DRI Proteomics Platform (1)
University of Nebraska Medical Center School of Medicine Department of Genetics, Cell Biology, & Anatomy Buckley Lab Omaha, Nebraska United States of America (1)
Division of Hematology, Department of Medicine, University of Colorado Anschutz, Aurora, CO, USA (1)
Research Group on Stem Cell Aging Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) Beutenbergstraße 11 07745 Jena, Germany (1)
Molecular Proteomics Laboratory, Biomedical Research Center (BMFZ), Heinrich-Heine-University, Düsseldorf, Germany (1)
Sanquin Research, Amsterdam, NL (1)
Division of Genome Sciences and Cancer, The John Curtin School of Medical Research, The Australian National University, Canberra (1)
Faculty of Science, Engineering & Medicine, School of Life Sciences, University of Sussex, United Kingdom (1)
Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland (1)
UCLA (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
SR-TIGET (1)
Functional Proteomics, ICR (1)

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Aberrant chromatin acetylation in MLL-AF9 leukemia mediates the response to HDAC inhibition (ChIP-Seq)

We studied the chromatin modification patterns induced by the presence of the MLL-AF9 fusion protein in a model of human hematopoietic stem/progenitor cells (HSPC) transduced with retrovirus expressing MLL-AF9cDNA (HSPC-MA9). Comparative ChIP-seq analysis between HSPC-MA9 and control HSPC, revealed ...

ORGANISM(S): Homo sapiens

2015-03-01 | E-GEOD-54344 | biostudies-arrayexpress

Jarid2 regulates hematopoietic stem cell function by acting with Polycomb Repressive Complex 2

Polycomb Repressive Complex 2 (PRC2) has been shown to play a key role in hematopoietic stem and progenitor cell (HSPC) function. Analyses of mouse mutants harboring deletions of core components have implicated PRC2 in fine-tuning multiple pathways that instruct HSPC behavior, yet how PRC2 is target...

ORGANISM(S): Mus musculus

2015-04-02 | E-GEOD-60808 | biostudies-arrayexpress

HSPC scRNA seq

PRJNA627730 | ENA

HSPC and CRPC

Genetic alteration between HSPC and CRPC

PRJEB32473 | ENA

RNA-seq for Healthy HSPC

PRJNA1083471 | ENA

Microarray Analysis of Cohesin Mutant HSPC

Transciptome analysis of CD34+ enriched human HSPC lentivirally transduced with cohesin WT or mutant CD34+ enriched HSPCs from cord blood were transduced with a constitutive lentiviral vector expressing cohesin WT or mutant tagged to GFP. After 72hrs cells were GFP+ sorted and subjected to downstrea...

ORGANISM(S): Homo sapiens

2015-11-03 | E-GEOD-73224 | biostudies-arrayexpress

RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE]

PRJNA437152 | ENA

Transcriptome analysis of HSPC, THP1 and K562 cells under IFNɑ treatment

HSPC harbor constitutively active antiviral blocks that can be induced by type I IFN in certain cell types such as THP-1 cells but not in the K562 cell line. In the effort to identify such factors we compared trascriptomes from HSPC, THP1 and K562 stimulated or not with type I IFN

ORGANISM(S): Homo sapiens

2023-03-05 | E-MTAB-6598 | biostudies-arrayexpress

RNA-seq of MLLT3-L and MLLT3-S overexpressing cultured HSPC, compared to non-overexpressing and uncultured FL-HSPC

PRJNA1058624 | ENA

KLF7 KO vs WT HSPC expression array

Increased expression of Kruppel like factor 7 (KLF7) is an independent predictor of poor outcome in pediatric acute lymphoblastic leukemia. The contribution of KLF7 to hematopoiesis has not been previously described. Herein, we characterized the effect on murine hematopoiesis of the loss of KLF7 and...

ORGANISM(S): Mus musculus

2012-08-24 | E-GEOD-40323 | biostudies-arrayexpress

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2428 Results

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