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TranscriptomicsTranscription profiling of human HT1080 fibrosarcoma cells treated with cytostatic drugs
HT1080 fibrosarcoma cells were treated with cytostatic drugs and analysed on Affymetrix microarray to identify genes and pathways regulated by these compounds. The array images were processed using Affymetrix MAS 5.0 software. and normalized by global scaling or scaled to a polyA+ spike mask
ORGANISM(S): Homo sapiens 
2008-04-01 | E-GEOD-2238 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of HT1080 fibrosarcoma cells of mesenchymal or amoeboid migratory phenotype
Amoeboid and mesenchymal migration of cancer cells both contribute to metastatic spreading of tumors. To characterize gene expression profiles underlying the different migratory modes, we performed RNA sequencing of HT1080 fibrosarcoma cells undergoing mesenchymal-amoeboid transition induced by eith...
ORGANISM(S): Homo sapiens 
2019-07-29 | E-MTAB-6823 | biostudies-arrayexpress
GenomicsTranscriptional outcome of telomere elongation in human fibrosarcoma model
Transcriptional outcome of telomere elongation in human fibrosarcoma model
PRJNA1112864 | ENA
ProteomicsQuantitative proteomics upon Fentomycin treatment VS untreated in human fibrosarcoma HT1080 cells
Our data of mass spectrometry-based lipidomics showed that fentomycin induced the oxidation of membrane lipids in HT-1080 cells compared with the established ferroptosis inducers. To deepen this discovery, we performed quantitative mass spectrometry-based proteomics using the sublethal dose of fento...
ORGANISM(S): Homo sapiens (Human) 
2025-03-06 | PXD054449 | Pride
Fentomycin Proteome Fibrosarcoma Ferroptosis 
TranscriptomicsTranscription profiling of human ermal lymphatic endothelial cells (LEC) with those isolated from tumours of murine T241/VEGF-C/GFP metastatic fibrosarcoma reveals lymphatic endothelium of metastatic tumours has a distinct transcription profile.
Invasion of lymphatic vessels is a key step in the metastasis of primary tumour cells to draining lymph nodes. Recent evidence indicates that such metastasis can be facilitated by tumour lymphangiogenesis, although it remains unclear whether this is a consequence of increased lymphatic vessel number...
ORGANISM(S): Mus musculus 
2008-10-25 | E-GEOD-6255 | biostudies-arrayexpress
TranscriptomicsTRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in human fibrosarcoma cells.
Microarray analysis revealed differential gene expression patterns of HT1080 cells treated with various chemical compounds alone and in combination (trabectedin, doxorubicin, mafosfamide, TRAIL, taurolidine) Microarray analysis of HT1080 cells treated with various chemical compounds alone and in com...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-32441 | biostudies-arrayexpress
GenomicsEpigenomics analysis of a fibrosarcoma with ESCC case
Epigenomics analysis of a fibrosarcoma with ESCC case
PRJNA438955 | ENA
TranscriptomicsExpression analysis of human CRABP1 gene and R131A CRABP1 mutant in HT1080 cells
Investigation of whole genome gene expression level changes in HT1080 fibrosarcoma cell line after transfection CRABP1 gene and R131A CRABP1 mutant (arginine-alanine substitution in a protein active site, protein lacks the ability to interact with retinoic acid), compared to HT1080 line transfected ...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-48673 | biostudies-arrayexpress
GenomicsTime-dependent expression data from human fibrosarcoma human cell line (HT1080) in collagen matrix with protease inhibitors
Time-dependent expression data from human fibrosarcoma human cell line (HT1080) in collagen matrix with protease inhibitors
PRJNA809927 | ENA
TranscriptomicsTranscriptional outcome of telomere elongation in human fibrosarcoma model
The study focuses on understanding the transcriptional changes and the pathways altered when human cancer (fibrosarcoma ) cells are subjected to telomere elongation.
ORGANISM(S): Homo sapiens 
2024-05-18 | GSE267781 | GEO
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