Sort   by:  
 Page size 
ProteomicsAbsolute quantification of human milk caseins and the whey/casein ratio during the first year of lactation
Whey proteins and caseins in breast milk provide bioactivities and also have different amino acid composition. Accurate determination of these two major protein classes will therefore provide a better understanding of human milk composition and function and also aid in developing improved infant for...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-06-23 | MSV000081195 | MassIVE
MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
ProteomicsImproving fractionation of human milk proteins through calcium phosphate co-precipitation and their rapid characterization by capillary electrophoresis
This work describes a simple sample pretreatment method for the fractionation of human milk proteins (into their two main groups: whey and caseins) prior to their analysis. The protein extraction protocol is based on the addition of calcium phosphate to non-adjusted pH human milk. The combination of...
ORGANISM(S): Homo sapiens (Human) 
2018-08-31 | PXD010315 | Pride
Calcium phosphate fractionation  human milk whey proteins  human milk caseins  capillary electrophoresis  fraction collection 
ProteomicsDiscovery and quantification of non-human proteins in human milk
The question whether and which non-human peptides or proteins are present in human milk was raised many decades ago. However, due to cross-reactivity or nonspecific antibody recognition, the accuracy of detection by immunochemical methods has been a concern. Additionally, the relative low-abundance ...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Felis catus (Cat) (Felis silvestris catus) Canis familiaris (Dog) (Canis lupus familiaris) Gallus gallus (Chicken) Oryza sativa (Rice) Equus caballus (Horse) 
2018-12-04 | PXD011599 | Pride
Non-human peptides Shotgun proteomics Human milk Mass spectrometry Non-human proteins Parallel reaction monitoring 
ProteomicsDiscovery and quantification of non-human proteins in human milk
The question whether and which non-human peptides or proteins are present in human milk was raised many decades ago. However, due to cross-reactivity or nonspecific antibody recognition, the accuracy of detection by immunochemical methods has been a concern. Additionally, the relative low-abundance ...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Felis catus (Cat) (Felis silvestris catus) Canis familiaris (Dog) (Canis lupus familiaris) Gallus gallus (Chicken) Oryza sativa (Rice) Equus caballus (Horse) 
2020-11-04 | PXD010413 | Pride
Non-human peptides Shotgun proteomics Human milk Mass spectrometry Non-human proteins Parallel reaction monitoring 
ProteomicsAntibody-independent identification of bovine milk-derived peptides in breast-milk
Exclusively breast-fed infants can exhibit clear signs of IgE or non IgE-mediated cow’s milk allergy. The definite characterization of dietary cow’s milk proteins (CMP) that survive the maternal digestive tract to be absorbed into the bloodstream and secreted into breast milk remains missing. The ai...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-02 | MSV000080880 | MassIVE
ProteomicsChanges over lactation in breast milk serum proteins.
The objective of this study is to investigate the changes of the breast milk proteome from four individual mothers over a six month lactation period by shotgun proteomic techniques, because a comprehensive understanding of the human milk proteome may lead to better understanding of the needs of infa...
ORGANISM(S): Homo sapiens (Human) 
2016-02-12 | PXD003465 | Pride
Human milk nlc-msms proteomics 
UnknownMilk Containing A2 β-Casein ONLY, as a Single Meal, Causes Fewer Symptoms of Lactose Intolerance than Milk Containing A1 and A2 β-Caseins in Subjects with Lactose Maldigestion and Intolerance: A Randomized, Double-Blind, Crossover Trial.
Not available
S-EPMC7766938 | biostudies-literature
UnknownCaseins: Versatility of Their Micellar Organization in Relation to the Functional and Nutritional Properties of Milk.
Not available
S-EPMC10004547 | biostudies-literature
ProteomicsMilking it? Assessing the degradation of ancient milk proteomes
The origins, prevalence and nature of dairying have been long debated by archaeologists. Within the last decade, new advances in high-resolution mass spectrometry have allowed for the direct detection of milk proteins from archaeological remains, including ceramics, dental calculus, and preserved da...
ORGANISM(S): Homo sapiens (Human) 
2021-08-05 | PXD022368 | Pride
Milk Authentication Palaeoproteomics Deamidation 
Sort   by:  
 Page size