Sort   by:  
 Page size 
MetabolomicsAssociation between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease

Chagas disease causes a cardiac illness characterized by immunoinflammatory reactions leading to myocardial fibrosis and remodeling. The development of Chronic Chagas Cardiomyopathy (CCC) in some patients while others remain asymptomatic is not fully understood, but dysregulated inflammatory resp...

2024-01-11 | MTBLS8390 | MetaboLights
MetabolomicsNew insights into the responses of soil microorganisms to polycyclic aromatic hydrocarbon stress by combining enzyme activity and sequencing analysis with metabolomics
Polycyclic aromatic hydrocarbons (PAHs), some of the most widespread organic contaminants, are highly toxic to soil microorganisms. Whether long-term polluted soils can still respond to the fresh input of pollutants is unknown. In this study, the soil enzyme activity, soil microbial community struct...
2021-02-17 | MTBLS1196 | MetaboLights
ProteomicsComparative proteomics of Marinobacter sp. TT1 reveals Corexit impacts on hydrocarbon metabolism, chemotactic motility and biofilm formation
The application of chemical dispersants during marine oil spills can affect the community composition and activity of native marine microorganisms. Several studies have indicated that certain marine hydrocarbon-degrading bacteria, such as Marinobacter spp., can be inhibited by chemical dispersants, ...
ORGANISM(S): Marinobacter sp. DSM 26291 
2020-12-22 | PXD021108 | Pride
Marinobacter sp. tt1  dispersant  corexit  waf  hexadecane  hydrocarbon metabolism  proteomics 
MetabolomicsMulti-omics analysis revealed the aromatic compound metabolism in marine Roseobacter clade

Here, we selected Roseovarius nubinhibens as the model organism to comprehensively interrogate aromatic compound metabolism in marine Roseobacter clade. First, we preliminarily elucidated the three distinct mechanisms of aromatic compound transmembrane transport in R. nubinhibens. By integrating ...

2025-08-09 | MTBLS12306 | MetaboLights
ProteomicsProfiling Tryptophan Catabolites of Human Gut Microbiota and Acute-Phase Protein Levels in Neonatal Dried Blood Specimens
National screening programs use dried blood specimens to detect abnormal metabolism or aberrant protein function in infants shortly after birth, thus identifying disorders that are not clinically evident in the newborn period. Gut microbiota metabolites and immunological acute phase proteins are cap...
ORGANISM(S): Homo Sapiens 
2022-08-02 | PXD027606 | panorama
MetabolomicsTryptophan Metabolism and AHR Signaling in the Intraocular Fluid of Uveitis: An Exploratory Study Integrating Metabolomics, Single-Cell Transcriptomics, Molecular Docking, and Mendelian Randomization within a Gut–Eye Axis Framework
Uveitis is a highly heterogeneous intraocular inflammatory disease, and recurrent attacks can lead to irreversible visual impairment. Gut microbiota may contribute to its pathogenesis through metabolic products and immune modulation, but existing evidence is largely derived from cross-sectional asso...
2026-08-28 | MTBLS15487 | MetaboLights
ProteomicsC. testosteroni aromatic compound metabolism
Data comparing protein expression during growth of Comamonas testosteroni Kf1 on succinate with growth on 3 aromatic substrates (vanillate, terephthalate, 4-hydroxybenzoate). Quantification by diDO-IPTL (Waldbauer et al. 2017 Analytical Chemistry).
ORGANISM(S): Comamonas Testosteroni Kf-1 (ncbitaxon:399795) 
2021-11-19 | MSV000088418 | MassIVE
MetabolomicsC2C12 stretch cessation models muscle atrophy and anaplerotic changes in metabolism
Not available
ORGANISM(S): Mus musculus 
ST000431 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of mouse Langerhans cells from aryl hydrocarbon receptor deficient mice
The arylhydrocarbon receptor is a ligand inducible transcription factor. Known to control xenobiotic metabolizing enzymes, it also affects - depending on the cell type - numerous other genes, either directly or indirectly. With respect to the immune system, persistent activation leads to immunosuppr...
ORGANISM(S): Mus musculus 
2009-11-16 | E-GEOD-13130 | biostudies-arrayexpress
MetabolomicsAnalysis of the effects of Tyrosine Kinase Inhibitors Sunitinib and Erlotinib on Muscle Metabolism In Vivo
Not available
ORGANISM(S): Mus musculus 
ST000896 | MetabolomicsWorkbench
Sort   by:  
 Page size