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MetabolomicsMetabolic-engineered probiotic-OMVs as nanovaccine mediating sequential immunomodulation for chronic bone infection immunotherapy

Chronic, drug-resistant bone infection caused by methicillin-resistant Staphylococcus aureus (MRSA) features an immunosuppressive niche enabling persistent infection and impaired bone healing. Specific treatment requires initial antibacterial immune activation against infection, followed by resha...

2026-03-19 | MTBLS14091 | MetaboLights
MetabolomicsMetabolic interactions of “catecholamine-cholesterol derivatives” as a potential mechanism for immunomodulation of chicken adipose tissue

In recent years, the immunomodulatory function of adipose tissue has attracted much attention; however, the mechanism of steady-state regulation of the immune microenvironment in adipose tissue remains unclear. Catecholamines (CAs) activate adipocyte surface β3-AR to promote lipid metabolism, and...

2025-07-15 | MTBLS12719 | MetaboLights
MetabolomicsPolyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells (Part 3)
Not available
ORGANISM(S): Mus musculus 
ST001998 | MetabolomicsWorkbench
MetabolomicsPolyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells (Part 2)
Not available
ORGANISM(S): Mus musculus 
ST001997 | MetabolomicsWorkbench
MetabolomicsPolyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells (Part 1)
Not available
ORGANISM(S): Mus musculus 
ST001996 | MetabolomicsWorkbench
MetabolomicsPolyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells (Part 4)
Not available
ORGANISM(S): Mus musculus 
ST001999 | MetabolomicsWorkbench
GenomicsRv1906c mediated host immunomodulation
Rv1906c mediated host immunomodulation in mice model of TB infection
PRJEB64201 | ENA
ProteomicsConserved immunomodulation and variation in host association by Xanthomonadales commensals in Arabidopsis root microbiota
Suppression of chronic Arabidopsis immune responses is a widespread but typically strain-specific trait across the major bacterial lineages of the plant microbiota. Here, through phylogenetic analysis of 1,765 Xanthomonadales genomes, we show that immunomodulation is a highly conserved, ancestral tr...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-12-12 | PXD045054 | Pride
Innate immunity Xanthomonadales Clearance of immunogenic peptide Immunomodulation Plant microbiota 
ClinicalLocal Immunomodulation After Radiofrequency of Unresectable Colorectal Liver Metastases
The main objective of this trial is to determine feasibility and tolerance of the human body to RFA associated with local immunomodulation carried out using a thermoreversible hydrogel combined with 2 immunomodulators, GMCSF and Mifamurtide. The main endpoint of the study is the feasibility, the fre...
2314216 | ecrin-mdr-crc
Genomicsimmunomodulation via human enteric viruses
Human enteric viruses shape disease phenotype through divergent innate immunomodulation
PRJEB44121 | ENA
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