inheritance - OmicsDI

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CHEBI ID

CHEBI:30769 (46)
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Metabolite Name

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Lab affiliation

Dpt. of Immunobiology University of Lausanne (UNIL), Boveresses 155 CH-1066 Epalinges (4)
Novo Nordisk Foundation Center for Protein Research (CPR), University of Copenhagen, Copenhagen, Denmark. (2)
Head of Laboratory of Neuro-Oncology, Neurology, Clinical & Cancer Proteomics (2)
Head of the Curie Institute Mass Spectrometry Platform (2)
Biomedical Center, Chromatin Proteomics Group, Department of Molecular Biology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhaderner Strasse 9, 82152 Planegg-Martinsried, Germany. (1)
Leibniz Institute on Aging - Fritz Lipmann Institute FLI (1)
Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK (1)
Research Institute of Tsinghua University, Shenzhen (1)
Max Planck Institute for Heart and Lung Research, Laboratory for Cell Polarity and Organogenesis, Germany (1)
Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Switzerland (1)
1. Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Germany 2. Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany (1)
Division of Cancer Cell Biology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan (1)
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne, Cologne, Germany. (1)
Department of Gene Expression, Faculty of Biology, Adam Mickiewicz University in Poznan, Poznan, Poland (1)
CSIR-Centre for Cellular and Molceular Biology, Hyderabad, India TIGS-Tata Institute for Genetics and Society ,Bengaluru, India (1)
Department of Biology, University of North Dakota, Grand Forks, ND 58202, USA. (1)
Jennifer Van Eyk, PhD, FAHA and FISHR Director, Advanced Clinical Biosystems Research Institute Professor, Heart Institute and Department of Medicine, Director, Basic Science for the Barbra Streisand Women's Heart Center Erika Glazer Endowed Chair in Women Heart Cedars Sinai Medical Center 127 S. San Vicente Blvd. Advanced Health Science Pavilion A9307 Los Angeles, CA 90048 and Professor, Departments of Medicine and Biological Chemistry, Johns Hopkins University (1)
Jennifer Van Eyk, PhD, FAHA and FISHR Director, Advanced Clinical Biosystems Research Institute Professor, Heart Institute and Department of Medicine, Director, Basic Science for the Barbra Streisand Women's Heart Center Erika Glazer Endowed Chair in Women Heart Cedars Sinai Medical Center 127 S. San Vicente Blvd. Advanced Health Science Pavilion A9307 Los Angeles, CA 90048 and Professor, Departments of Medicine and Biological Chemistry, Johns Hopkins University Baltimore (1)
Department of Physiology University of Pennsylvania Perelman School of Medicine 635 Clinical Research Building 415 Curie Boulevard Philadelphia, PA 19104-6058 (1)
Indiana University School of Medicine, USA (1)
1Molecular Cell Biology, Institute of Cell Biology, University of Tübingen (1)
Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China (1)
Plant Physiology. Organisms and systems biology. University of Oviedo (1)
Center for Epigenetics Van Andel Research Institute Grand Rapics, Michigan 49503, USA (1)
Professor of Parasite Molecular Biology Biological Chemistry and Drug Discovery Wellcome Centre for Anti-Infectives Research (WCAIR) School of Life Sciences, University of Dundee (1)
Department of Cell Biology Harvard Medical School Boston, MA USA (1)
Institute of Cell Biology, University of Bern, Bern, Switzerland (1)
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany; Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany; Cardio-Pulmonary Institute, Frankfurt am Main, Germany (1)
Zentrallabor fuer Proteinanalytik BMC - LMU Munich Schillerstrasse 44 Munich D-80336 Germany (1)
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Ingolstädter Landstr. 1 D-85764 Neuherberg Germany (1)

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A nuclear Argonaute promotes germline immortality and epigenetic inheritance across generations

dsRNA-mediated gene silencing (RNAi) can be inherited for multiple generations in C. elegans. To understand this process we conducted a genetic screen for animals defective for transmitting RNAi silencing signals to future generations. This screen identified the gene heritable RNAi defective (hrde)-...

ORGANISM(S): Caenorhabditis elegans

2012-07-30 | E-GEOD-38041 | biostudies-arrayexpress

Genetic stability and germ cell epigenetic instability in the Mtrr mouse model of transgenerational epigenetic inheritance.

Folate metabolism is important for DNA synthesis and repair through its role in the synthesis of the nucleotide thymidine. Mice with a hypomorphic mutation in the gene Mtrr have disrupted folate metabolism and show transgenerational inheritance of developmental abnormalities. We sought to explore if...

ORGANISM(S): Mus musculus

2021-04-06 | E-MTAB-8513 | biostudies-arrayexpress

Mrc1 facilitates epigenetic inheritance through proper parental histone segregation

Chromatin-based epigenetic memory relies on the equal distribution of parental histone tetramers, which serve as templates for duplicating parental chromatin, to newly synthesized daughter DNA strands. Histone chaperones within the replisome, such as the histone binding domains (HBDs) of Mcm2 and Po...

ORGANISM(S): Schizosaccharomyces Pombe (ncbitaxon:4896)

2023-07-16 | MSV000092452 | MassIVE

Germ cell epigenetic instability in the Mtrr mouse model of transgenerational epigenetic inheritance

Folate metabolism is important for the generation of methyl groups required for cellular methylation reactions. Mice with a hypomorphic mutation in the gene Mtrr have disrupted folate metabolism and show transgenerational inheritance of developmental abnormalities. We sought to explore if DNA methyl...

ORGANISM(S): Mus musculus

2021-04-06 | E-MTAB-8533 | biostudies-arrayexpress

Dioxin (TCDD) Induces Epigenetic Transgenerational Inheritance of Adult Onset Disease and Sperm Epimutations

Environmental compounds can promote epigenetic transgenerational inheritance of adult-onset disease in subsequent generations following ancestral exposure during fetal gonadal sex determination. The current study examined the ability of dioxin (2,3,7,8-tetrachlorodibenzo[p]dioxin, TCDD) to promote e...

ORGANISM(S): Rattus norvegicus

2014-07-22 | E-GEOD-59552 | biostudies-arrayexpress

Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease [NimbleGen]

The actions of environmental toxicants and relevant mixtures in promoting the epigenetic transgenerational inheritance of ovarian disease was investigated with the use of a fungicide, a pesticide mixture, a plastic mixture, dioxin and a hydrocarbon mixture. After transient exposure of an F0 gestatin...

ORGANISM(S): Rattus norvegicus

2014-07-17 | E-GEOD-59277 | biostudies-arrayexpress

Hydrocarbons (Jet Fuel JP-8) Induce Epigenetic Transgenerational Inheritance of Obesity, Reproductive Disease and Sperm Epimutations

Environmental compounds have been shown to promote epigenetic transgenerational inheritance of disease. The current study was designed to determine if a hydrocarbon mixture involving jet fuel (JP-8) promotes epigenetic transgenerational inheritance of disease. Gestating F0 generation female rats wer...

ORGANISM(S): Rattus norvegicus

2014-07-22 | E-GEOD-59553 | biostudies-arrayexpress

Pesticide and Insect Repellent Mixture (Permethrin and DEET) Induces Epigenetic Transgenerational Inheritance of Disease and Sperm Epimutations

Environmental compounds are known to promote epigenetic transgenerational inheritance of disease. The current study was designed to determine if a M-bM-^@M-^\pesticide mixtureM-bM-^@M-^] (pesticide permethrin and insect repellent N,N-Diethyl-meta-toluamide, DEET) promotes epigenetic transgenerationa...

ORGANISM(S): Rattus norvegicus

2014-07-22 | E-GEOD-59554 | biostudies-arrayexpress

Expression-inheritance

Gene expression inheritance in hybrids

PRJEB7565 | ENA

Environmentally induced epigenetic transgenerational inheritance of ovarian disease

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Rattus norvegicus

2014-07-17 | E-GEOD-59278 | biostudies-arrayexpress

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