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TranscriptomicsPSN1 Polysome and INK128
Polysome-bound mRNA was analyzed to determine the effects of INK128 and radiation on mRNA translation 4 samples were analyzed with 3 biological replicates
ORGANISM(S): Homo sapiens 
2014-02-03 | E-GEOD-48098 | biostudies-arrayexpress
TranscriptomicsPSN1 Polysome and INK128
Polysome-bound mRNA was analyzed to determine the effects of INK128 and radiation on mRNA translation
ORGANISM(S): Homo sapiens 
2014-02-03 | GSE48098 | GEO
TranscriptomicsDistinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma
The mechanistic target of rapamycin, (mTOR) kinase plays a pivotal role in controlling critical cellular growth and survival pathways, and its aberrant induction is implicated in cancer pathogenesis. Therefore, suppression of active mTOR signaling has been of great interest to researchers; several m...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-62790 | biostudies-arrayexpress
GenomicsmTOR inhibition by INK128 extends ovarian functions in aging and premature aging mice following germline stem cell transplantation
mTOR inhibition by INK128 extends ovarian functions in aging and premature aging mice following germline stem cell transplantation
PRJNA660943 | ENA
UnknownCD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128.
Not available
S-EPMC5995255 | biostudies-literature
UnknownDistinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma.
Not available
S-EPMC4350884 | biostudies-literature
UnknownThe ATP-competitive mTOR inhibitor INK128 enhances in vitro and in vivo radiosensitivity of pancreatic carcinoma cells.
Not available
S-EPMC3947297 | biostudies-literature
UnknownMtor inhibition by INK128 extends functions of the ovary reconstituted from germline stem cells in aging and premature aging mice.
Not available
S-EPMC7884035 | biostudies-literature
GenomicsHomo sapiens
PSN1 Polysome and INK128
PRJNA208930 | ENA
TranscriptomicsmTOR inhibition by INK128 extends ovarian functions in aging and premature aging mice following germline stem cell transplantation
Germline stem cell transplantation in combination with mTOR inhibition by INK128 can improve and extend ovarian and endocrine functions of aging and particularly premature aging mice.
ORGANISM(S): Mus musculus 
2020-09-08 | GSE157325 | GEO
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