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Genomicsmouse metagenome strain:K18-hACE2
Mouse metagenome strain:K18-hACE2 Raw sequence reads
PRJNA722991 | ENA
GenomicsMus musculus musculus strain:K18-hACE2 | breed:C57BL/6
Effect of Mac1 deletion mutant of SARS-CoV-2 infection of K18-hACE2 mice
PRJNA928501 | ENA
ProteomicsFunctional Heterogeneity Analysis of Mesenchymal Stem Cell Lines and their Therapeutic Potential in the K18-hACE2 Mouse Model of SARS-CoV-2 Infection
Despite many years of investigation into mesenchymal stem cells (MSCs) and their potential for treating inflammatory conditions such as COVID-19, clinical outcomes remain variable due to factors like donor variability, different tissue sources, and diversity within MSC populations. Variations in MSC...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD051984 | Pride
Covid-19  k18-hace2 Immunomodulation Mesenchymal stem cells  heterogeneity 
ProteomicsMulti-organ proteomic and phosphoproteomic landscape of K18-hACE2 mice infected with SARS-CoV-2
Eight 10-week-old female K18-hACE2 mice were equally divided into control (n = 4) and virus-infected group (n = 4). Mice in the virus-infected group were challenged with 10^5 median tissue culture infective dose (TCID50) of SARS-CoV-2 virus by intranasal inoculation and mice in the control group wer...
ORGANISM(S): Mus Musculus 
2022-07-21 | PXD035474 |
GenomicsTranscriptional profiling of lungs from SARS-CoV-2-infected K18-hACE2 mice
Transcriptional profiling of lungs from SARS-CoV-2-infected K18-hACE2 mice
PRJNA1072723 | ENA
TranscriptomicsDelta (B1.617.2) variant of SARS-CoV-2 induces severe neurotropic patterns in K18-hACE2 mice
To investigated neurotropic patterns between the B1.617.2 (Delta) and Hu-1 variants (Wuhan early strain) in K18-hACE2 mice.
ORGANISM(S): Mus musculus 
2023-03-08 | GSE214516 | GEO
ProteomicsGlobal Analysis of Lysine Acetylation in the Brain Cortex of K18-hACE2 Mice Infected with SARS-CoV-2
In order to research the relationship between neurological sequelae of COVID-19 and acetylation of brain cortexes, we reported for the first time the acetylome in the brain cortex of the K18-hACE2 infected mouse model, and the difference between the SARS-CoV-2 infection group and the control group, ...
ORGANISM(S): Mus Musculus 
2022-09-20 | PXD036853 |
GenomicsDelta (B1.617.2) variant of SARS-CoV-2 induces severe neurotropic patterns in K18-hACE2 mice
Delta (B1.617.2) variant of SARS-CoV-2 induces severe neurotropic patterns in K18-hACE2 mice
PRJNA885792 | ENA
TranscriptomicsTranscriptional profiling of lungs from SARS-CoV-2-infected K18-hACE2 mice
To explore the effects of SARS-CoV-2 proteins on expression of host genes in lung of infected mice, 4 groups of K18-hACE2 mice (4 mice per group) were mock-infected or infected cells with SARS-CoV-2 WT or its NPS1, or NSP15 mutants respectively.The mice were euthanized at 4 days post-infection to co...
ORGANISM(S): Mus musculus 
2025-02-01 | GSE254969 | GEO
UnknownHuman convalescent plasma protects K18-hACE2 mice against severe respiratory disease.
Not available
S-EPMC8295914 | biostudies-literature
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