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Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine,UPMC Hillman Cancer Center, Pittsburgh, PA
(1)
Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109
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Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA
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University of Oxford, Nuffield Department of Medicine, Target Discovery Institute
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Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury
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Tags
xref:PubMed:19650929
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xref:PubMed:33204712
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xref:PubMed:26040664
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Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by activating a shunt pathway that generates the toxic metabolite 24(S),25-epoxycholesterol
LUM2_708738 - MM0299-probe bound protein; LUM2_708739 - MM0299 competition; LUM2_850369 - Ro-alkyne bound protein; LUM2_850370 - Ro 48-8071 competition
ORGANISM(S):
Mus Musculus (ncbitaxon:10090)
2023-01-11
|
MSV000091046
|
MassIVE
Cite
Functional characterization and localization of Pneumocystis carinii lanosterol synthase.
Not available
S-EPMC2805306
|
biostudies-literature
Cite
Lanosterol Synthase Prevents EMT During Lens Epithelial Fibrosis Via Regulating SREBP1.
Not available
S-EPMC10715316
|
biostudies-literature
Cite
Lanosterol Synthase Gene Polymorphisms and Changes in Endogenous Ouabain in the Response to Low Sodium Intake.
Not available
S-EPMC4713326
|
biostudies-literature
Cite
Ocular delivery of lipid nanoparticles-formulated mRNA encoding lanosterol synthase ameliorates cataract in rats.
Not available
S-EPMC12474983
|
biostudies-literature
Cite
Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation.
Not available
S-EPMC8217109
|
biostudies-literature
Cite
Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis.
Not available
S-EPMC2621255
|
biostudies-literature
Cite
Inhibition of lanosterol synthase linking with MAPK/JNK signaling pathway suppresses endometrial cancer.
Not available
S-EPMC11807098
|
biostudies-literature
Cite
Using genetics to investigate the association between lanosterol and cataract.
Not available
S-EPMC10910428
|
biostudies-literature
Cite
Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by activating a shunt pathway that generates the toxic metabolite 24(S),25-epoxycholesterol
Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by activating a shunt pathway that generates the toxic metabolite 24(S),25-epoxycholesterol
PRJNA924316
|
ENA
Cite
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