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MetabolomicsLong-term low-dose ionizing radiation induced chromosome-aberration-specific metabolic phenotype changes in radiation workers

Long-term low-dose ionizing radiation (LLIR) widely exists in human life and has been confirmed to have potential pathogenic effects on cancer and cardiovascular diseases. However, it is technically and ethically unfeasible to explore LLIR-induced phenotypic changes in the human cohort, leading t...

2022-04-07 | MTBLS3854 | MetaboLights
MetabolomicsEffect of external low-dose rate radiation on mouse biofluid metabolomic signatures (part I)
Not available
ORGANISM(S): Mus musculus 
ST001790 | MetabolomicsWorkbench
MetabolomicsEffect of external low-dose rate radiation on mouse biofluid metabolomic signatures (part IV)
Not available
ORGANISM(S): Mus musculus 
ST001793 | MetabolomicsWorkbench
MetabolomicsEffect of external low-dose rate radiation on mouse biofluid metabolomic signatures (part III)
Not available
ORGANISM(S): Mus musculus 
ST001792 | MetabolomicsWorkbench
MetabolomicsEffect of external low-dose rate radiation on mouse biofluid metabolomic signatures (part II)
Not available
ORGANISM(S): Mus musculus 
ST001791 | MetabolomicsWorkbench
MetabolomicsEffect of external low-dose rate radiation on mouse biofluid metabolomic signatures (part V)
Not available
ORGANISM(S): Mus musculus 
ST001806 | MetabolomicsWorkbench
TranscriptomicsExpression data in mouse liver exposed to low dose-rate radiation
Expression profiles in mouse liver exposed to long-term gamma-irradiation were examined to assess in vivo effects of low dose-rate radiation. Three groups of male C57BL/6J mice were exposed to whole body irradiation at dose-rates of 17-20 mGy/day, 0.86-1.0 mGy/day or 0.042-0.050 mGy/day for 401-485 ...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-20562 | biostudies-arrayexpress
TranscriptomicsGenetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility.
This study investigates three radiation exposure scenarios in BALB/c and C57BL/6 mice: (1) low dose (LD) group -- four weekly doses of 7.5 cGy, (2) high dose (HD) group -- four weekly doses of 1.8 Gy, (3) unexposed group -- four weekly sham exposures. We then used comparative expression profiles of ...
ORGANISM(S): Mus musculus 
2012-11-01 | E-GEOD-40066 | biostudies-arrayexpress
TranscriptomicsResponse to low dose ionizing radiation in male mouse
Male mice 10-14 weeks of age were exposed in vivo to 10 rad X-ray. The objective is to extract information on gene networks from the microarray data. Control mice were sham-exposed. Spleen was harvested 3.5 hrs post-irradiation. Each hybridization consists of one control mouse and one exposed mou...
ORGANISM(S): Mus musculus 
2006-10-01 | E-GEOD-4880 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of human umbilical vein endothelial cells (HUVECs) chronically irradiated with low dose-rate of ionizing radiation for one, three and six weeks.
To obtain more insight in the molecular effects of chronic low dose irradiation on endothelial cells, HUVEC were irradiated with low-dose rate irradiation (137Cs gamma source; 0, 1.4 and 4.1 mGy/h) for several weeks. At different time points (1, 3 and 6 weeks) cells were harvested for RNA extraction...
ORGANISM(S): Homo sapiens 
2018-02-28 | E-MTAB-6521 | biostudies-arrayexpress
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