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ProteomicsCardiac perilipin 5 promotes physiological cardioprotective hypertrophy through increased calcium handling and cardiomyocyte contractility
: The adult heart develops hypertrophy to reduce ventricular wall stress and maintain cardiac function in response to an increased workload. Although pathological hypertrophy generally progresses to heart failure, physiological hypertrophy may be cardioprotective. Cardiac-specific overexpression of ...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-20 | PXD035121 | Pride
Perilipin 5  mhc-plin5  physiological hypertrophy  calcium signaling  serca2. 
TranscriptomicsCardiomyocyte specific plin5 over expression
Presence of ectopic lipid droplets (LDs) in cardiac muscle is associated to lipotoxicity and tissue dysfunction. However, presence of LDs in heart is also observed in physiological conditions, such as at times when cellular energy needs and energy production from mitochondria fatty acid (FA) ?-oxid...
ORGANISM(S): Mus musculus 
2013-02-09 | E-GEOD-44192 | biostudies-arrayexpress
TranscriptomicsCardiomyocyte specific plin5 over expression
Presence of ectopic lipid droplets (LDs) in cardiac muscle is associated to lipotoxicity and tissue dysfunction. However, presence of LDs in heart is also observed in physiological conditions, such as at times when cellular energy needs and energy production from mitochondria fatty acid (FA) β-oxida...
ORGANISM(S): Mus musculus 
2013-02-09 | GSE44192 | GEO
UnknownCardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility.
Not available
S-EPMC9887753 | biostudies-literature
UnknownCardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction.
Not available
S-EPMC3606001 | biostudies-literature
GenomicsMus musculus
Cardiomyocyte specific plin5 over expression
PRJNA189050 | ENA
UnknownCardiac lipid droplets differ under pathological and physiological conditions.
Not available
S-EPMC12617763 | biostudies-literature
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