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MetabolomicsGenotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness
Diet may be modified seasonally or by biogeographic, demographic or cultural shifts. It can differentially influence mitochondrial bioenergetics, retrograde signalling to the nuclear genome, and anterograde signalling to mitochondria. All these interactions have the potential to influence the freque...
2018-11-07 | MTBLS724 | MetaboLights
TranscriptomicsInsights into N-calls of mitochondrial DNA sequencing using MitoChip v2.0
Background: Developments in DNA resequencing microarrays include mitochondrial DNA (mtDNA) sequencing and mutation detection. During automated analysis to sequence mtDNA, bases can be identified as wildtype, variant, or there may be a failure to assign a base (N-call) when compared to the mtDNA refe...
ORGANISM(S): Homo sapiens 
2012-05-17 | E-GEOD-29550 | biostudies-arrayexpress
ProteomicsHaplotype variability in mitochondrial rRNA predisposes to metabolic syndrome
Metabolic syndrome is a growing concern in developed societies and due to its polygenic nature, the genetic component is only slowly being elucidated. Common mitochondrial DNA sequence variants have been associated with symptoms of metabolic syndrome and may therefore be relevant players in the gene...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-08-13 | PXD052976 | Pride
Metabolic syndrome Diacylglycerols Mitochondrial haplotype Insulin signaling 
TranscriptomicsMitochondrial haplotype dependant T cell activity
Mitochondrial haplotype dependant T cell activity
ORGANISM(S): Mus musculus 
2024-12-19 | GSE276714 | GEO
GenomicsMitochondrial haplotype dependant T cell activity
Mitochondrial haplotype dependant T cell activity
PRJNA1158737 | ENA
TranscriptomicsMitochondrial haplotype influences ovarian aging in genetically heterogeneous rats
Ovarian aging leads to permanent reproductive senescence and systemic hormonal changes that predispose to age-associated comorbidities. Despite these clinical implications, the intrinsic mechanisms driving age-related ovarian decline are poorly defined. Mitochondrial DNA (mtDNA) mutations and instab...
ORGANISM(S): Rattus norvegicus 
2026-09-17 | GSE328056 | GEO
GenomicsMitochondrial haplotype influences ovarian aging in genetically heterogeneous rats
Mitochondrial haplotype influences ovarian aging in genetically heterogeneous rats
PRJNA1453584 | ENA
UnknownIdentification of an X-chromosomal locus and haplotype modulating the phenotype of a mitochondrial DNA disorder.
Not available
S-EPMC1285165 | biostudies-literature
ProteomicsPhysiological variability in mitochondrial rRNA may predispose to metabolic syndrome
Objectives: Metabolic syndrome and its associated comorbidities are a growing concern in developed societies. Due to its polygenic nature, the genetic component of metabolic syndrome is only slowly being elucidated. Common mitochondrial DNA sequence variants have been associated with late-onset huma...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-08-13 | PXD045910 | Pride
Metabolic syndrome  mitochondrial haplotype  diacylglycerols  insulin signaling 
GenomicsCanis lupus mitochondrial genome
Canis lupus haplotype 27 D-loop, partial sequence, mitochondrial
PRJEB97977 | ENA
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