Three-dimensional (3D) cell culture technologies, which more closely mimic the complex microenvironment of tissue, are being increasingly evaluated as a tool for the preclinical screening of clinically promising new molecules, and studying of tissue metabolism. Studies of metabolites released int...

Cell culture is generally considered to be hyperoxic. However, the importance of cellular oxygen consumption is often underappreciated, with rates of oxygen consumption often sufficient to cause hypoxia at cell monolayers. We initially focused on cultured adipocytes as a terminally differentiated...

Epichloë sinensis, associated with Festuca sinensis, exhibits rich morphological, genetic and functional diversity across different strains. To comprehensively evaluate the categories and difference in the secondary metabolites of different E. sinensis strains and thereby...

This study employed untargeted metabolomics detection combined with bioinformatics analysis to investigate the metabolites from the co-culture of Acinetobacter lwoffiiand cervical precancerous cells ECT1/E6E7. A. lwoffiiwas co-cultured with ECT1/E6E7 cells at an MOI of 100. The culture supernatan...