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Each organ of the human body requires locally-adapted blood vessels1–3. The gain of such organotypic vessel specializations is often deemed molecularly unrelated to the process of organ vascularization. Opposing this model, we reveal a molecular mechanism for brain-specific angiogenesis that operate...
ORGANISM(S): Homo sapiens (Human) 
2024-02-08 | PXD042613 | Pride
We partnered with Zymo Research, Inc. to detect genome-wide methylation changes associated with the initiation and progression of tendinopathy induced by TGF-β1 in a murine Achilles tendon model. All genes identified as significantly differentially methylated were present in only one experimental gr...
ORGANISM(S): Mus musculus 
2016-08-17 | GSE80396 | GEO
Here, we describe new information on changes in the lncRNA landscape and their potential role in the pathogenesis of HIV/SIV induced intestinal epithelial dysfunction. Our study provides relevant novel insights on the protective role of the natural anti-sense lncRNA MMP25-AS1 in the colonic epitheli...
ORGANISM(S): Homo sapiens Macaca mulatta 
2023-02-28 | GSE223482 | GEO
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