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TranscriptomicsNIH3T3 transfected with myocardin
NIH3T3 cell transiently transfected with myocardin-EGFP or EGFP. Transfection: Lipofectamine 2000 according to the manufacturers instructions (Invitrogen).
ORGANISM(S): Mus musculus 
2013-11-15 | E-MEXP-3869 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human skeletal myoblasts misexpressing myocardin
transcriptional effects of mis-expression of full length (935) myocardin in growing human skeletal myoblasts Experiment Overall Design: Compare transcriptional profiles of Ad-myocardin infected SKM5 cells with that of Ad-B-gal infected cells
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3378 | biostudies-arrayexpress
TranscriptomicsMyocardin-related Transcription Factors Are Required for Skeletal Muscle Development
Myocardin-related transcription factors (MRTFs) play a central role in the regulation of actin expression and cytoskeletal dynamics. Stimuli that promote actin polymerization allow for shuttling of MRTFs to the nucleus where they activate serum response factor (SRF), a regulator of actin and other c...
ORGANISM(S): Mus musculus 
2016-08-02 | E-GEOD-84063 | biostudies-arrayexpress
TranscriptomicsmiRNAs were significantly regulated by myocardin and ERM-NM-1
Using microarray, we compared miRNAs expression profiles of MDA-MB-231 cells transfected with myocardin and empty vector (pcDNA3.1) and found that 25 miRNAs were significantly changed in myocardin-transfected groups (17 up-regulated and 9 down-regulated miRNAs). Moreover, we showed that 18 of 25 miR...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-44139 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Analysis of Gene Program Activation by Defined Cardiac Transcription Factor Tbx5, Gata4 and Myocardin
Background: Cardiac transcription factors are master regulators during heart development. Recently, some were shown to transdifferentiate noncardiac mesoderm cells and cardiac fibroblasts into cardiomyocytes. However, the individual roles of each transcription factors in activating cardiac gene prog...
ORGANISM(S): Mus musculus 
2012-11-30 | E-GEOD-27329 | biostudies-arrayexpress
GenomicsGenome-wide DNA-binding analysis for Myocardin in human lung cancer cell line A549
Genome-wide DNA-binding analysis for Myocardin in human lung cancer cell line A549
PRJNA529788 | ENA
TranscriptomicsMyocardin-like Protein (MKL)-2 Regulates TGF-β Signaling in Embryonic Stem Cells and the Developing Vasculature
Signal transduction from the extracellular matrix to the arterial wall plays a critical role during development of the vasculature. We now report the discovery of a Myocardin-like Protein (MKL)2/TGF-β signaling pathway that is required for maturation and stabilization of the vasculature. Mkl2-/- n...
ORGANISM(S): Mus musculus 
2012-05-31 | E-GEOD-38316 | biostudies-arrayexpress
UnknownMyocardin and myocardin-related transcription factor-A synergistically mediate actin cytoskeletal-dependent inhibition of liver fibrogenesis.
Not available
S-EPMC7099496 | biostudies-literature
TranscriptomicsGene expression profiling of overexpression of myocardin
ABSTRACT Aims Forced differentiation of non-muscle cells into heart muscle cells using cardiac transcription factors (cTFs) may constitute a novel strategy to accomplish myocardial regeneration. Methods We investigated the potential of the cTF myocardin to induce cardiomyocyte differentiation and co...
ORGANISM(S): Homo sapiens 
2008-07-15 | GSE12110 | GEO
GenomicsSpatial expression of Myocardin protein in normal and disease states
Spatial expression of Myocardin protein
PRJEB105946 | ENA
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