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MetabolomicsAirway metabolic profiling during Streptococcus pneumoniae infection identifies branched chain amino acids as signatures of upper airway colonisation

Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and bacteraemia and is capable of remarkable phenotypic plasticity, responding rapidly to environmental change. Pneumococcus is a nasopharyngeal commensal, but is responsible for severe, acute infections followin...

2023-08-08 | MTBLS4591 | MetaboLights
TranscriptomicsM. catarrhalis Gene Expression in the Chinchilla Nasopharynx
M. catarrhalis strain O35E.rpsl was inoculated into the nasopharynx of healthy, male adult chinchillas. 24 hours later the nasopharyngeal tissues were extracted and homogenized. Total RNA was extracted from these tissue samples. Subsequently, M. catarrhalis genome directed primers were utilized t...
ORGANISM(S): Moraxella catarrhalis 
2012-04-03 | E-GEOD-13559 | biostudies-arrayexpress
ProteomicsLC-MSMSMass Spectrometric detection of SARS-CoV-2 virus in scrapings of the epithelium of the nasopharynx of infected patients via Nucleocapsid N protein
Detection of viral RNA by PCR is currently the main diagnostic tool for COVID-191. The PCR-based test, however, shows limited sensitivity, especially at early and late stages of the disease development, and is relatively time consuming. Fast and reliable complementary methods for detecting the viral...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2020-08-14 | PXD019648 | Pride
Covid Covid-19 Proteomics Sars-cov-2 
MetabolomicsThe influence of Pseudomonas aeruginosa infection on the airway metabolome
Pseudomonas aeruginosa is an environmentally resilient bacterium and an important cause of both acute and chronic infections in people with impaired natural barriers or immunological defences. Chronic respiratory infection with P. aeruginosa is a major cause of morbidity and mortality in people with...
2025-11-06 | MTBLS6052 | MetaboLights
GenomicsNasopharynx, Oropharynx swabs and oral wash raw sequence fast reads
Nasopharynx, Oropharynx swabs and oral wash raw sequence fast reads Metagenome
PRJNA820027 | ENA
GenomicNasopharynx Cancer Whole Exome Sequencing

Nasopharyngeal carcinoma (NPC) is an aggressive head and neck cancer characterized by Epstein-Barr virus (EBV) infection and dense lymphocyte infiltration. The scarcity of NPC genomic data hinders the understanding of NPC biology, disease progression, and rational therapy design. Here, we perform...

phs001244 | dbGaP
GenomicsNasopharynx Cancer Whole Exome Sequencing
Nasopharynx Cancer Whole Exome Sequencing
PRJNA353541 | ENA
TranscriptomicsExpression data from human nasopharynx cell line transfected with gene or empty vector.
We used microarrays to detail the global gene expression in human nasopharynx cell line transfected with gene or empty vector.
ORGANISM(S): Homo sapiens 
2015-04-01 | GSE67456 | GEO
TranscriptomicsExpression data from human nasopharynx cell line transfected with gene or empty vector.
We used microarrays to detail the global gene expression in human nasopharynx cell line transfected with gene or empty vector. human nasopharynx cell line transfected with gene or empty vector were for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-67456 | biostudies-arrayexpress
Genomicshuman nasopharyngeal metagenome
Human nasopharynx Metagenome
PRJNA229922 | ENA
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