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GenomicsNext Generation Sequencing of Newly excysted juveniles, Juveniles and Adult Fasciola hepatica
Next Generation Sequencing of Newly excysted juveniles, Juveniles and Adult Fasciola hepatica
PRJNA776863 | ENA
ProteomicsThe host factor: proteomic comparison of excretion/1 secretion products in Fasciola hepatica newly excysted juveniles (NEJ) derived from Lymnaea viatrix or Pseudosuccinea columella
The characteristics of parasitic infections are often tied to host behavior. Although most studies have investigated definitive hosts, intermediate hosts can also play a role in shaping the distribution and accumulation of parasites. This is particularly relevant in larval stages, where intermediate...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2019-04-30 | PXD011991 | Pride
Parasite-host interaction Fasciola hepatica Intermediate host Secretome 
ProteomicsStudy of the migration of Fasciola hepatica juveniles across the intestinal barrier of the host by quantitative proteomics in an ex vivo model
The project presents the set-up of an ex vivo model coupled with quantitative SWATH-MS proteomics to study the early events following the passage of Fasciola hepatica Newly Excysted Juveniles (NEJ) though the host’s intestinal wall, assessing the proteomic changes in their surface (tegument) and som...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2022-08-31 | PXD033945 | Pride
Fasciola hepatica  newly excysted juveniles  gut passage  swath-ms  quantitative proteomics  differential expression 
GenomicsNext Generation Sequencing of Newly excysted juveniles, Juveniles and Adult Fasciola hepatica
Purpose: The miRnome of the liver fluke, Fasciola hepatica, has historically been assembled with limited omic's resources using specific life stages. The goals of this study is to quanity the known and published miRNAs and determine novel miRNAs across three intra-mammlian life stages. Methods: Tota...
ORGANISM(S): Fasciola hepatica 
2022-05-31 | GSE186948 | GEO
ProteomicsProteomics coupled with in vitro model to study the early crosstalk occurring between newly excysted juveniles of Fasciola hepatica and host intestinal cells
Here, we develop a new in vitro model replicating the first interaction of FhNEJ with mouse primary small intestinal epithelial cells (MPSIEC). FhNEJ and MPSIEC were incubated for 3 hours and protein extracts (tegument and soma for FhNEJ and membrane and cytosol for MPSIEC) were subjected to quantit...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2022-09-20 | PXD033952 | Pride
Fasciola hepatica  newly excysted juveniles  swath-ms  quantitative proteomics  differential expression  host-parasite interaction 
UnknownRNA interference in Fasciola gigantica: Establishing and optimization of experimental RNAi in the newly excysted juveniles of the fluke.
Not available
S-EPMC5749881 | biostudies-literature
UnknownDataset supporting the proteomic differences found between excretion/secretion products from two isolates of Fasciola hepatica newly excysted juveniles (NEJ) derived from different snail hosts.
Not available
S-EPMC6661421 | biostudies-literature
UnknownBinding and cleavage of pro-urokinase by a tegument extract of Fasciola hepatica newly excysted juveniles activate the host fibrinolytic system.
Not available
S-EPMC11762853 | biostudies-literature
UnknownProteomics coupled with in vitro model to study the early crosstalk occurring between newly excysted juveniles of Fasciola hepatica and host intestinal cells.
Not available
S-EPMC9555655 | biostudies-literature
UnknownIn vitro co-culture of <i>Fasciola hepatica</i> newly excysted juveniles (NEJs) with 3D HepG2 spheroids permits novel investigation of host-parasite interactions.
Not available
S-EPMC11938319 | biostudies-literature
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