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GenomicsAnalysis of NFE2L2 (NRF2) binding to chromatin in primary human keratinocytes
Analysis of NFE2L2 (NRF2) binding to chromatin in primary human keratinocytes
PRJNA633526 | ENA
GenomicsPatient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggesssive Murine Hepatoblastomas
Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggesssive Murine Hepatoblastomas
PRJNA662245 | ENA
GenomicsAnalysis of NFE2L2 (NRF2) binding to chromatin in primary human keratinocytes
Analysis of NFE2L2 (NRF2) binding to chromatin in primary human keratinocytes
ORGANISM(S): Homo sapiens 
2021-03-31 | GSE150760 | GEO
UnknownActivating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder.
Not available
S-EPMC5635015 | biostudies-literature
UnknownTranscription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.
Not available
S-EPMC5079676 | biostudies-literature
TranscriptomicsPatient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggesssive Murine Hepatoblastomas
The pediatric liver cancer hepatoblastoma (HB) often expresses mutant forms of b-catenin and dysregulates the Hippo tumor suppressor pathway. Murine HBs can be generated by co-expressing b-catenin mutants and the constitutively active Hippo effector YAPS127A. Some human HBs also express mutant forms...
ORGANISM(S): Mus musculus 
2021-05-20 | GSE157623 | GEO
UnknownPatient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas.
Not available
S-EPMC8102178 | biostudies-literature
UnknownTranscription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A.
Not available
S-EPMC6103698 | biostudies-literature
TranscriptomicsGene expression profiling of neutrophils and whole lung tissue from wildtype and Nrf2 null (Nfe2l2-/-) mice during S. pneumoniae pneumonia [neutrophils]
The transcription factor Nrf2 (gene symbol Nfe2l2) regulates the transcriptional response to oxidative stress and plays a critical protective role in the lungs. These studies tested the role of Nrf2 during pneumonia induced by Streptococcus pneumoniae (SP) at 24 hours in mice and identified Nrf2-dep...
ORGANISM(S): Mus musculus 
2016-09-09 | GSE83613 | GEO
GenomicsIdentification of Novel NRF2-Regulated Genes by ChIPSeq
Cellular oxidative and electrophilic stress triggers a protective response in mammals regulated by NRF2 (nuclear factor (erythroid-derived) 2-like; NFE2L2) binding to DNA-regulatory sequences near stress responsive genes. Studies using Nrf2-deficient mice suggest that hundreds of genes may be regula...
ORGANISM(S): Homo sapiens 
2012-06-18 | E-GEOD-37589 | biostudies-arrayexpress
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