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TranscriptomicsMycobacterial cells have dual nickel-cobalt sensors: sequence-relationships and metal-sites of metal-responsive repressors are not congruent.
A novel ArsR-SmtB family transcriptional repressor, KmtR, has been characterised from mycobacteria. Mutants of M. tuberculosis lacking kmtR show elevated expression of Rv2025c encoding a deduced CDF-family metal-exporter. KmtR-dependent repression of the cdf and kmtR operator-promoters was alleviate...
ORGANISM(S): Mycobacterium tuberculosis 
2007-09-17 | E-BUGS-49 | biostudies-arrayexpress
GenomicsSphingobium Nickel resistance analysis by RNA-seq approach
Sphingobium Nickel resistance analysis by RNA-seq approach
PRJEB21342 | ENA
TranscriptomicsSphingobium Nickel resistance analysis by RNA-seq approach
Nickel is an essential component of many eukaryotic and prokaryotic metallo-enzymes. Due to its employment in many industrial applications, wastewaters from industrial plants often contain millimolar concentrations of Ni2+ that are toxic and life-threatening for many organism. Several lines of pre...
ORGANISM(S): Sphingobium sp. ba1 
2017-07-03 | E-MTAB-5828 | biostudies-arrayexpress
ProteomicsExtracellular proteins enhance Cupriavidus pauculus nickel tolerance and cell aggregate formation
Heavy metal-resistant bacteria secrete extracellular proteins (e-PNs). However, the role of e-PNs in heavy metal resistance remains elusive. Here Fourier Transform Infrared Spectroscopy implied that N-H, C = O and NH2-R played a crucial role in the adsorption and resistance of Ni2+ in the model orga...
ORGANISM(S): Cupriavidus pauculus 
2023-12-21 | PXD045082 | Pride
Extracellular proteins  cupriavidus pauculus  nickel resistance  secretome  efflux pumps 
TranscriptomicsTranscriptomic analysis of a nickel-resistant Saccharomyces cerevisiae mutant obtained by evolutionary engineering
Nickel-resistant Saccharomyces cerevisiae mutant was obtained by evolutionary engineering. The reference strain which was used to select this nickel-resistant mutant could not grow even at 0.5 mM NiCl2 whereas this mutant was shown to be resistant upto 5.3 mM NiCl2 concentration. Whole-genome microa...
ORGANISM(S): Saccharomyces cerevisiae 
2013-09-19 | GSE50985 | GEO
UnknownNreB from Achromobacter xylosoxidans 31A Is a nickel-induced transporter conferring nickel resistance.
Not available
S-EPMC99496 | biostudies-literature
TranscriptomicsTranscriptomic analysis of a nickel-resistant Saccharomyces cerevisiae mutant obtained by evolutionary engineering
Nickel-resistant Saccharomyces cerevisiae mutant was obtained by evolutionary engineering. The reference strain which was used to select this nickel-resistant mutant could not grow even at 0.5 mM NiCl2 whereas this mutant was shown to be resistant upto 5.3 mM NiCl2 concentration. Whole-genome microa...
ORGANISM(S): Saccharomyces cerevisiae 
2013-09-19 | E-GEOD-50985 | biostudies-arrayexpress
TranscriptomicsTranscriptomics data on E. coli lacking queuosine tRNA modification (tgt deficient strain) exposed or not to nickel stress.
Purpose: to observe differences in E. coli transcripts levels due to the absence of the tRNA modification queuosine and due to exposure to excess nickel. Methods: RNAseq was performed using the total RNA isolated from E. coli MG1655 WT and Δtgt strains grown in LB medium only or in LB added by 2 mM ...
ORGANISM(S): Escherichia coli 
2022-05-15 | GSE181239 | GEO
UnknownNickel and cobalt resistance engineered in Escherichia coli by overexpression of serine acetyltransferase from the nickel hyperaccumulator plant Thlaspi goesingense.
Not available
S-EPMC1317400 | biostudies-literature
UnknownNickel-resistance-based minitransposons: new tools for genetic manipulation of environmental bacteria.
Not available
S-EPMC92686 | biostudies-literature
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