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ProteomicsProteomic profiling of mouse brain pyruvate kinase binding proteins: a hint for moonlighting functions of PKM1?
Affinity based proteomic profiling is widely used for identification of proteins involved in for-mation of various interactomes. Pyruvate kinase (PK), a classical glycolytic enzyme catalyzing the last step of glycolysis, exists in four isoforms, one of which, PKM2; pyruvate kinase muscle isoform M2 ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD041321 | Pride
Pyruvapyruvate kinase  pyruvate kinase isoforms  pkm  non-canonical moonlighting functions  pkm-binding proteins  interactomete kinase  pyruvate kinase isoforms  pkm  non-canonical moonlighting functions  pkm-binding proteins  interactome 
UnknownMultiple chaperonins in bacteria--novel functions and non-canonical behaviors.
Not available
S-EPMC4463927 | biostudies-literature
UnknownMulti-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1.
Not available
S-EPMC8282090 | biostudies-literature
UnknownActin Depolymerization Factor (ADF) Moonlighting: Nuclear Immune Regulation by Interacting with WRKY Transcription Factors and Shaping the Transcriptome.
Not available
S-EPMC12393267 | biostudies-literature
UnknownStructural variability of multifunctional proteins indicates frequent stochastic evolution of protein oligomers.
Not available
S-EPMC12749353 | biostudies-literature
UnknownBeyond energy: how TCA cycle-derived metabolites regulate gene expression and inflammation in the nucleus.
Not available
S-EPMC12465655 | biostudies-literature
UnknownThe Diverse Functional Roles of Elongation Factor Tu (EF-Tu) in Microbial Pathogenesis.
Not available
S-EPMC6822514 | biostudies-literature
TranscriptomicsPGK1 moonlights as an NF-kB/p65 kinase to orchestrate M2-like macrophage-mediated immunosuppression in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is the most aggressive molecular subtype with limited therapeutic options. Metabolic reprogramming is a hallmark of cancer, and emerging evidence indicates metabolic enzymes possess non-canonical moonlighting functions. We identified phosphoglycerate kinase 1 (PG...
ORGANISM(S): Mus musculus 
2026-08-06 | GSE341921 | GEO
UnknownThe many roles of the eukaryotic elongation factor 1 complex.
Not available
S-EPMC3374885 | biostudies-literature
UnknownAminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis.
Not available
S-EPMC8914993 | biostudies-literature
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