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Olfactory ensheathing cells are one of the few central nervous system regenerative cells discovered so far. It is characterized by its lifelong nerve regeneration function, and it can also release a variety of neurotrophic factors and neural adhesion molecules. It is considered to be the glial cell ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD024046 | Pride
This experiment investigates differences in miRNA expression between different populations of human mesenchymal stem cells (MSCs), which are a potential treatment for multiple sclerosis (MS). Previously it has been reported that MSCs derived from human olfactory mucosa (OM-MSCs) may be a better cand...
ORGANISM(S): Homo sapiens 
The aim of this study was to use global gene expression profiling to define intrinsic molecular differences that distinguish olfactory ensheathing cells from mucosa (OM-OECs) from olfactory ensheathing cells from olfactory bulb (OB-OECs). 10,000 OECs from olfactory mucosa (OM) or olfactory bulb (OB)...
ORGANISM(S): Rattus norvegicus 
2009-12-02 | GSE19250 | GEO
The recent development of next-generation sequencing (NGS) techniques encouraged us to assess the transcriptome of the murine OE. We analyzed RNA from OEs of female and male adult mice and from fluorescence-activated cell sorting (FACS)-sorted olfactory receptor neurons (ORNs) obtained from transgen...
ORGANISM(S): Mus musculus 
The olfactory mucosa (OM) has the unique characteristic of pursuing almost continuous neurogeneration during adulthood in response to external injuries to maintain olfactory function due to the presence of stem cells. The easily accessibility of the OM in humans is a feature that makes these stem ce...
ORGANISM(S): Homo sapiens 
2017-03-17 | GSE96737 | GEO
In this work, we demonstrate that neonatal mice infected with ZIKV via intracranial injection suffers from transient olfactory dysfunction when they grow up to puberty. Moreover, ZIKV exhibits broad cellular tropism and mainly targets the olfactory ensheathing cells (OECs) in the olfactory mucosa (O...
ORGANISM(S): Mus musculus 
2022-10-03 | GSE214567 | GEO
Next Generation Sequencing Facilitates Quantitative Analysis of Mock/ZIKV Infected AG6 Mice Olfactory Mucosa and Olfactory Bulb Transcriptomes
To gain a global view of the effect of systematic glucocorticoid treatment on gene expression in the olfactory mucosa (OM), we profiled these changes in a murine model of olfaction in order to identify underlying molecular mechanisms.
ORGANISM(S): Mus musculus 
2015-05-31 | GSE68151 | GEO
Total RNA sequencing of olfactory mucosa (OM) cells derived from cognitively healthy individuals exposed to traffic-related ultrafine particles (UFPs) for 24h and 72h in submerged cultures. The UFPs used for exposures were: A0, A20 and Euro6. Exposures were compared to the corresponding blank sample...
Comparative Gene Expression Profiling of Olfactory Ensheathing Cells from Olfactory Bulb and Olfactory Mucosa
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