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GenomicsFluvastatin protects Leydig cells in orchitis through direct activation of Peroxiredoxin 1
Fluvastatin protects Leydig cells in orchitis through direct activation of Peroxiredoxin 1
PRJNA1268478 | ENA
TranscriptomicsFluvastatin protects Leydig cells in orchitis through direct activation of Peroxiredoxin 1
Orchitis caused by infection is one of the most important causes of male infertility, which can cause an imbalance of the oxidation/antioxidation system. Appropriate antioxidant therapy may be effective in alleviating testicular damage. Previous studies found that peroxiredoxin 1 (PRDX1) is involved...
ORGANISM(S): Mus musculus 
2025-12-03 | GSE298181 | GEO
UnknownAmiodarone induced epididymo-orchitis.
Not available
S-EPMC6556547 | biostudies-literature
UnknownGasdermin D in macrophages drives orchitis by regulating inflammation and antigen presentation processes.
Not available
S-EPMC10897472 | biostudies-literature
GenomicsMicrobiota-derived acetate protects against UPEC-epididymo-orchitis by improving the phagocytosis of testicular macrophages.
Microbiota-derived acetate protects against UPEC-epididymo-orchitis by improving the phagocytosis of testicular macrophages.
PRJNA1184345 | ENA
TranscriptomicsMicrobiota-derived acetate protects against UPEC-epididymo-orchitis by improving the phagocytosis of testicular macrophages.
The gut microbiota is intimately associated with maintaining a stable intestinal immune balance. However, it remains unclear whether gut dysbiosis affects the homeostasis within the testes. In our DSS-induced colitis mouse model, we observed increased inflammatory cell infiltration within the mouse ...
ORGANISM(S): Mus musculus 
2025-05-01 | GSE281537 | GEO
UnknownBone Status in a Mouse Model of Experimental Autoimmune-Orchitis.
Not available
S-EPMC8346031 | biostudies-literature
UnknownOrchitis: a complication of severe acute respiratory syndrome (SARS).
Not available
S-EPMC7109827 | biostudies-literature
UnknownManagement of epididymo-orchitis in primary care: results from a large UK primary care database.
Not available
S-EPMC2944950 | biostudies-literature
UnknownMelatonin Ameliorates Inflammation and Oxidative Stress by Suppressing the p38MAPK Signaling Pathway in LPS-Induced Sheep Orchitis.
Not available
S-EPMC7765110 | biostudies-literature
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