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GenomicsPolycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity
We report that the PRC1 component polycomb group ring finger 6 (Pcgf6) is required to maintain embryonic stem cell (ESC) identity. In contrast to canonical PRC1, Pcgf6 acts as a positive regulator of transcription and binds predominantly to promoters bearing active chromatin marks. Pcgf6 is expres...
ORGANISM(S): Mus musculus 
2016-07-28 | E-GEOD-84905 | biostudies-arrayexpress
TranscriptomicsPCGF6, a polycomb group protein, regulates mesodermal lineage differentiation in murine ES cells and functions in iPS reprogramming
Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main multiprotein polycomb repressive complexes (PRC1 and PRC2) that operate in a hierarchical manner to sil...
ORGANISM(S): Mus musculus 
2014-09-26 | E-GEOD-56126 | biostudies-arrayexpress
GenomicsPcgf6 suppresses Myc-induced lymphomagenesis [ChIP-seq]
Pcgf6 suppresses Myc-induced lymphomagenesis [ChIP-seq]
PRJNA785540 | ENA
GenomicsPcgf6 suppresses Myc-induced lymphomagenesis [RNA-seq]
Pcgf6 suppresses Myc-induced lymphomagenesis [RNA-seq]
PRJNA785559 | ENA
GenomicsPCGF6 activates SOX2 and contributes to lineage differentiation of human pluripotent stem cells
PCGF6 activates SOX2 and contributes to lineage differentiation of human pluripotent stem cells
PRJNA726721 | ENA
UnknownPolycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity.
Not available
S-EPMC4888081 | biostudies-literature
UnknownPCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.
Not available
S-EPMC9357003 | biostudies-literature
UnknownPCGF6/MAX/KDM5D facilitates MAZ/CDK4 axis expression and pRCC progression by hypomethylation of the DNA promoter.
Not available
S-EPMC9996882 | biostudies-literature
UnknownPCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.
Not available
S-EPMC5375644 | biostudies-literature
UnknownPCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions.
Not available
S-EPMC6776568 | biostudies-literature
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