Sort   by:  
 Page size 
MetabolomicsMetabolomics Study of Serum and Urine Samples Reveals Metabolic Pathways and Biomarkers Associated with Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is a common medical condition among women and involves complicated diagnostics and controversial surgical management. The exact molecular mechanism underlying POP is poorly understood, especially at the metabolism level. To explore the metabolic mechanism underlying POP a...
2019-08-14 | MTBLS1033 | MetaboLights
MetabolomicsPessary Therapy Restores Vaginal Microbiome Homeostasis in Severe Pelvic Organ Prolapse: A Longitudinal Metagenomic and Metabolic Analysis
Pelvic organ prolapse (POP), affecting up to 50% of elderly women, disrupts vaginal microbial homeostasis, yet the impact of first-line pessary therapy on microbiome dynamics remains poorly characterized. This prospective cohort study employed metagenomic sequencing and clinical metrics to longitudi...
2025-07-16 | MTBLS12722 | MetaboLights
TranscriptomicsGene expression profile in pelvic organ prolapse
Introduction and Hypothesis: Identify processes contributing to pelvic organ prolapse (POP) by transcriptional profiling of pelvic connective tissue in conjunction with light microscopy. Methods: We performed a frequency matched case-control study of women undergoing hysterectomy. Total RNA, extract...
ORGANISM(S): Homo sapiens 
2008-09-19 | E-GEOD-12852 | biostudies-arrayexpress
ProteomicsHuman POP analysis - Proteomics of Uterosacral Ligament Connective Tissue from Women With and Without Pelvic Organ Prolapse
Purpose: Damage to the uterosacral ligaments is an important contributor to uterine and vaginal prolapse. The aim of this study was to identify differentially expressed proteins in the uterosacral ligaments of women with and without pelvic organ prolapse and analyze their relationships to cellular...
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD011467 | Pride
Ingenuity pathway analysis  itraq analysis  pelvic organ prolapse  uterosacral ligament Reproductive system 
GenomicUniversity of Utah Pelvic Organ Prolapse Disorder Study

The overall purpose of this University of Utah Pelvic Organ Prolapse Disorder Study was to identify and localize predisposition genes contributing to pelvic organ prolapse (POP). POP cases recruited for this study were identified by one of three methods: high-risk POP pedigree cases, POP sister p...

phs001439 | dbGaP
TranscriptomicsMicro-array analysis of the anterior vaginal wall from premenopausal patients with Pelvic Organ Prolapse (POP)
Pelvic organ prolapse (POP) is a common multifactorial disease in a heterogeneous population of women. Due to this heterogeneity, the underlying molecular mechanisms contributing to the pathogenesis of POP are still unclear. We sought to identify dysregulated pathways by comparing gene expression pr...
ORGANISM(S): Homo sapiens 
2015-07-31 | E-GEOD-53868 | biostudies-arrayexpress
GenomicsProfiles of Pelvic organ prolapse [miRNA-seq]
Profiles of Pelvic organ prolapse [miRNA-seq]
PRJNA858990 | ENA
GenomicsProfiles of Pelvic organ prolapse
Profiles of Pelvic organ prolapse
PRJNA859003 | ENA
GenomicsInvestigation of spontaneous pelvic organ prolapse in the rhesus macaque model
Investigation of spontaneous pelvic organ prolapse in the rhesus macaque model
PRJNA852604 | ENA
GenomicsThe change of vaginal microbiome associated with pelvic organ prolapse, pessary usage, and surgical intervention
The change of vaginal microbiome associated with pelvic organ prolapse, pessary usage, and surgical intervention
PRJEB61246 | ENA
Sort   by:  
 Page size