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ProteomicsProteomic-based analysis of hypoxia and physioxia responsive proteins and pathways in DLBCLProteomic-based analysis of hypoxia and physioxia responsive proteins and pathways in DLBCL
Hypoxia is damaging to normal cells as well as cancerous cells. Reports assessing hypoxia- and physioxia-induced global proteome changes in lymphoma are lacking. Here, we sought to explore how the proteome of diffuse large B-cell lymphoma (DLBCL) changes when cells are exposed to the acute hypoxic s...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026726 | Pride
Hypoxia  physioxia  diffuse large b-cell lymphoma (dlbcl)  b-cell non-hodgkin lymphomas  label-free quantitative proteomics  protein-protein interaction network (ppin)  cell stress 
UnknownPhysioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal.
Not available
S-EPMC9479026 | biostudies-literature
UnknownPhysioxia enhances T-cell development ex vivo from human hematopoietic stem and progenitor cells.
Not available
S-EPMC7901063 | biostudies-literature
UnknownPhysioxia Has a Beneficial Effect on Cartilage Matrix Production in Interleukin-1 Beta-Inhibited Mesenchymal Stem Cell Chondrogenesis.
Not available
S-EPMC6721827 | biostudies-literature
UnknownProteomic-Based Analysis of Hypoxia- and Physioxia-Responsive Proteins and Pathways in Diffuse Large B-Cell Lymphoma.
Not available
S-EPMC8392495 | biostudies-literature
UnknownFibronectin Adherent Cell Populations Derived From Avascular and Vascular Regions of the Meniscus Have Enhanced Clonogenicity and Differentiation Potential Under Physioxia.
Not available
S-EPMC8831898 | biostudies-literature
ProteomicsEffect of oxygen tension on MMTV-PyMT tumor cell kinome
Solid tumors are characterized by significantly lower oxygen (O2) levels. Despite this fact, routine preclinical cancer studies are performed under ambient O2 conditions. We have developed an experimental approach that allows us to collect, process and evaluate cancer and non-cancer cells under phys...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-08 | PXD046005 | Pride
Ambient Breast cancer Kinase inhibitor beads Physioxia Lapatinib 
TranscriptomicsBulk and single cell profing of CD45+ LSK cells collected from WT and TET2 deficient mice under normoxia and hypoxia (physioxia) conditions (CITE-SEQ)
Hematopoietic stem cells (HSCs) manifest impaired recovery and self-renewal with a concomitant increase in progenitor content (HPCs) when exposed to ambient air as opposed to physioxia. Mechanisms behind this distinction are poorly understood but have the potential to enhance HSC function for bone m...
ORGANISM(S): Mus musculus 
2022-01-07 | GSE192992 | GEO
TranscriptomicsBulk and single cell profiling of CD45+ LSK cells collected from WT and TET2 deficient mice under normoxia and hypoxia (physioxia) conditions (BULK RNA-SEQ)
Hematopoietic stem cells (HSCs) manifest impaired recovery and self-renewal with a concomitant increase in progenitor content (HPCs) when exposed to ambient air as opposed to physioxia. Mechanisms behind this distinction are poorly understood but have the potential to enhance HSC function for bone m...
ORGANISM(S): Mus musculus 
2022-01-07 | GSE192988 | GEO
UnknownPhysioxia Promotes the Articular Chondrocyte-Like Phenotype in Human Chondroprogenitor-Derived Self-Organized Tissue.
Not available
S-EPMC5792248 | biostudies-literature
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