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GenomicsChromatinized PKC-q directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells
Epithelial to mesenchymal transition (EMT) is activated during cancer invasion and metastasis, enriches for cancer stem cells (CSCs), and contributes to therapeutic resistance and disease recurrence. Signal transduction kinases play a pivotal role as chromatin-anchored proteins in eukaryotes. Here w...
ORGANISM(S): Homo sapiens 
2014-06-22 | E-GEOD-53320 | biostudies-arrayexpress
TranscriptomicsProtein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells
Unlike mouse embryonic stem (ES) cells, which are closely related to the inner cell mass, human ES cells appear to be more closely related to the later primitive ectoderm. For example, human ES cells and primitive ectoderm share a common epithelial morphology, growth factor requirements, and the po...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-33180 | biostudies-arrayexpress
TranscriptomicsRNAi profiling by array of human U2-OS cells transfected with PKC delta siRNA and then left untreated or treated with adriamycin
U2-OS cells were transfected with scramble siRNA or PKC delta siRNA, then left untreated or treated with 2 ug/ml adriamycin for 8 h.
ORGANISM(S): Homo sapiens 
2011-03-23 | E-MEXP-2643 | biostudies-arrayexpress
TranscriptomicsPKC isoforms - MDA-MB-231
PKCalpha, delta and epsilon were downregulated in MDA-MB-231 cells and mRNA expression was analyzed
ORGANISM(S): Homo sapiens 
2011-03-01 | E-MTAB-462 | biostudies-arrayexpress
GenomicsRegulation of inducible genes in epithelial to mesenchymal transition by chromatinized PKC-theta
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-06-22 | E-GEOD-53335 | biostudies-arrayexpress
GenomicsExogenous NAD+ induces mucin secretion in LS 174T goblet cells via the PLC-delta/PTGES/PKC-delta/ERK1/2/CREB signalling pathway
Exogenous NAD+ induces mucin secretion in LS 174T goblet cells via the PLC-delta/PTGES/PKC-delta/ERK1/2/CREB signalling pathway
PRJNA588296 | ENA
TranscriptomicsExogenous NAD+ induces mucin secretion in LS 174T goblet cells via the PLC-delta/PTGES/PKC-delta/ERK1/2/CREB signalling pathway
Mucin, one of family of glycoprotein that is a major component of the mucus layer in the intestine, is associated with antimicrobial activity and gut immune system function. Currently, mucin is mainly known for its critical function in defence against toxic molecules and pathogens. In this study, we...
ORGANISM(S): Homo sapiens 
2020-05-21 | GSE140116 | GEO
UnknownInhibition of PKC-δ reduce rhabdomyolysis-induced acute kidney injury.
Not available
S-EPMC9170808 | biostudies-literature
UnknownDetermination of the Role and Active Sites of PKC-Delta-Like from Lamprey in Innate Immunity.
Not available
S-EPMC6650827 | biostudies-literature
UnknownEffect of protein kinase C delta (PKC-δ) inhibition on the transcriptome of normal and systemic sclerosis human dermal fibroblasts in vitro.
Not available
S-EPMC3214051 | biostudies-literature
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